Evidence map›Paper›PMID 37502914›Full record

ArticlebioRxiv : the preprint server for biology2023

Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport.

Youjun Wu, Chen Ding, Alexis Weinreb, Laura Manning, Grace Swaim, Shaul Yogev, Daniel A Colón-Ramos, Marc Hammarlund

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Youjun WuDepartment of Genetics, Yale University School of Medicine, New Haven, CT 06536, USA.
Chen DingDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT 06536, USA.
Alexis WeinrebDepartment of Genetics, Yale University School of Medicine, New Haven, CT 06536, USA.
Laura ManningDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT 06536, USA.
Grace SwaimDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT 06536, USA.
Shaul YogevDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT 06536, USA.
Daniel A Colón-RamosDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT 06536, USA.
Marc HammarlundDepartment of Genetics, Yale University School of Medicine, New Haven, CT 06536, USA.
Yale University · US

Funding

New Mechanisms in Axon RegenerationR01NS094219 · NINDS · YALE UNIVERSITY · PI HAMMARLUND, MARC · 2015 to 2025
$4.0M
Patterning acentrosomal microtubule arraysR35GM133573 · NIGMS · YALE UNIVERSITY · PI Shaul Yogev · 2019 to 2026
$3.2M
Evaluation of Novel Axon Regeneration Targets for Spinal Cord injury TherapyR01NS098817 · NINDS · YALE UNIVERSITY · PI HAMMARLUND, MARC, STRITTMATTER, STEPHEN M · 2016 to 2020
$1.4M
NIGMS NIH HHS R35 GM133573NINDS NIH HHS R01 NS094219NINDS NIH HHS R01 NS098817
6 · The paper itself

Abstract

Mitochondria transport is crucial for mitochondria distribution in axons and is mediated by kinesin-1-based anterograde and dynein-based retrograde motor complexes. While Miro and Milton/TRAK were identified as key adaptors between mitochondria and kinesin-1, recent studies suggest the presence of additional mechanisms. In

Identifiers

PMID37502914
PMCPMC10369933
OpenAlexW4384133527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.