Evidence map›Paper›PMID 37502895›Full record

ArticlebioRxiv : the preprint server for biology2023

Protective intravenous BCG vaccination induces enhanced immune signaling in the airways.

Joshua M Peters, Edward B Irvine, Jacob M Rosenberg, Marc H Wadsworth, Travis K Hughes, Matthew Sutton, Sarah K Nyquist, Joshua D Bromley, Rajib Mondal, Mario Roederer and 7 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 20 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 1 country.

Joshua M Peters
Edward B Irvine
Jacob M Rosenberg
Marc H Wadsworth
Travis K Hughes
Matthew Sutton
Sarah K Nyquist
Joshua D Bromley
Rajib Mondal
Mario Roederer
Robert A Seder
Patricia A Darrah
Galit Alter
JoAnne L Flynn
Alex K Shalek
Sarah M Fortune
Bryan D BrysonORCID 0000-0003-1716-6712
Broad Institute · USHarvard University · USRagon Institute of MGH, MIT and Harvard · USBoston University · USHarvard–MIT Division of Health Sciences and Technology · USUniversity of Pittsburgh · US

Funding

Molecular Analysis of the Host Immune Response in LeprosyR01AI022553 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROBERT L MODLIN · 1989 to 2026
$15.7M
Dynamics of the cellular and molecular architecture of human pulmonary TB granulomasR01AI166313 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROBERT L MODLIN · 2022 to 2026
$3.2M
NIAID NIH HHS R01 AI022553NIAID NIH HHS R01 AI166313
6 · The paper itself

Abstract

Intradermal (ID) Bacillus Calmette-Guérin (BCG) is the most widely administered vaccine in the world. However, ID-BCG fails to achieve the level of protection needed in adults to alter the course of the tuberculosis epidemic. Recent studies in non-human primates have demonstrated high levels of protection against

Identifiers

PMID37502895
PMCPMC10370046
OpenAlexW4384666758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.