ArticlebioRxiv : the preprint server for biology2023
Associations between COVID-19 and putative markers of neuroinflammation: A diffusion basis spectrum imaging study.
Wei Zhang, Aaron J Gorelik, Qing Wang, Sara A Norton, Tamara Hershey, Arpana Agrawal, Janine D Bijsterbosch, Ryan Bogdan
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 2 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
8 authors at 2 institutions in 1 country.
Wei ZhangMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0001-6428-2033 Aaron J GorelikDepartment of Psychological & Brain Sciences, Washington University, St. Louis, MO, United States.ORCID 0000-0002-2589-1220 Qing WangMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, United States.
Sara A NortonDepartment of Psychological & Brain Sciences, Washington University, St. Louis, MO, United States.
Tamara HersheyMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, United States.
Arpana AgrawalDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.
Janine D BijsterboschMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, United States.
Ryan BogdanDepartment of Psychological & Brain Sciences, Washington University, St. Louis, MO, United States.
Washington University in St. Louis · USMallinckrodt (United States) · US
Funding
23/24 Healthy Brain and Child Development National ConsortiumU01DA055367 · NIDA · WASHINGTON UNIVERSITY · PI RYAN H BOGDAN, CYNTHIA Elise ROGERS · 2021 to 2026
$10.8MTRACKING NEURODEGENERATION IN EARLY WOLFRAM SYNDROMER01HD070855 · NICHD · WASHINGTON UNIVERSITY · PI HERSHEY, TAMARA G · 2012 to 2022
$5.6MQuantitative Endogenous MRI Imaging of Neuroinflammation in ADR01AG074909 · NIA · WASHINGTON UNIVERSITY · PI QING WANG · 2022 to 2026
$3.7MBrain Health Across the Metabolic Continuum in Youth at Risk for T2DR01DK126826 · NIDDK · WASHINGTON UNIVERSITY · PI ARSLANIAN, SILVA A, HERSHEY, TAMARA G · 2021 to 2025
$3.2MIntergenerational Transmission of Stress: Psychosocial and Biological MechanismsR01AG061162 · NIA · WASHINGTON UNIVERSITY · PI BOGDAN, RYAN H · 2019 to 2023
$3.1MCortical Network Modulation by Subthalamic Nucleus Deep Brain StimulationR01NS109487 · NINDS · WASHINGTON UNIVERSITY · PI CULVER, JOSEPH P, HERSHEY, TAMARA G · 2019 to 2024
$2.9MThe role of late life depression in cognitive decline and Alzheimer's Disease riskR01MH128286 · NIMH · WASHINGTON UNIVERSITY · PI Janine Diane Bijsterbosch · 2022 to 2026
$2.7MNeurobehavioral pathways of polygenic and polyenvironmental effects on the onset and maintenance of substance involvementR01DA054750 · NIDA · WASHINGTON UNIVERSITY · PI AGRAWAL, ARPANA, BOGDAN, RYAN H · 2021 to 2025
$2.0MModeling poly-genomic risk in the relationship between brain structure and alcohol involvement from adolescence through adulthoodR21AA027827 · NIAAA · WASHINGTON UNIVERSITY · PI BOGDAN, RYAN H · 2019 to 2020
$413kNIAAA NIH HHS R21 AA027827NIA NIH HHS R01 AG061162NIA NIH HHS R01 AG074909NICHD NIH HHS R01 HD070855NIDA NIH HHS R01 DA054750NIDA NIH HHS U01 DA055367NIDDK NIH HHS R01 DK126826NIMH NIH HHS R01 MH128286NINDS NIH HHS R01 NS109487
6 · The paper itselfAbstract
COVID-19 remains a significant international public health concern. Yet, the mechanisms through which symptomatology emerges remain poorly understood. While SARS-CoV-2 infection may induce prolonged inflammation within the central nervous system, the evidence primarily stems from limited small-scale case investigations. To address this gap, our study capitalized on longitudinal UK Biobank neuroimaging data acquired prior to and following COVID-19 testing (N=416 including n=224 COVID-19 cases; M
Indexed as
COVID-19DBSIDiffusion Basis Spectrum ImagingLong COVIDneuroimagingNeuroinflammationUK Biobank
Identifiers
PMID37502886
PMCPMC10370178
OpenAlexW4385067806
What OpenQuestion holds
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LicenceCC BY-NC-ND
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