ArticleFrontiers in nutrition2023
The protective effect of serum carotenoids on cardiovascular disease: a cross-sectional study from the general US adult population.
Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Pooled it
- Association Between Fruit and Vegetable Intake and Skin Carotenoid Levels Among Japanese Adults in the Workplace.Nutrients · 2026Article
- A comprehensive review of ischemic heart disease: pathophysiology, current treatments, natural products-based therapies, and nanotherapeutics.Frontiers in pharmacology · 2026Review
- Negative association between serum lutein/zeaxanthin levels and migraine in American adults: a retrospective study from NHANES.Archives of medical science : AMS · 2026Article
- Lutein Attenuates Synovial Hyperplasia, Cartilage Loss, and Bone Erosion by Suppressing Inflammatory Pathways in Rheumatoid Arthritis.International journal of medical sciences · 2026Article
- Skin and Macular Carotenoids in Relation to Brain Structure and Function in School-Aged Children.The Journal of nutrition · 2025Article
- Interaction effects of dietary carotenoid intake and gamma-glutamyl transferase level on the prevalence of stroke in older adults.Journal of health, population, and nutrition · 2025Observational
- Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive Function.The Journal of nutrition · 2025Article
- Creating an Improved Diatoxanthin Production Line by Knocking OutMarine drugs · 2025Article
- The Biologically Active Compounds in Fruits of Cultivated Varieties and Wild Species of Apples.Molecules (Basel, Switzerland) · 2025Review
- Association of serum carotenoids and SII among general people, based on NHANES 2001-2006.Scientific reports · 2025Article
- Carotenoids for Antiaging: Nutraceutical, Pharmaceutical, and Cosmeceutical Applications.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Unveiling roles of beneficial gut bacteria and optimal diets for health.Frontiers in microbiology · 2025Review
- Association between serum carotenoid concentrations and risk of major age-related eye diseases among middle-aged and older adults.Frontiers in medicine · 2025Article
- Marine Carotenoids: A Critical Review of Bioactivities, Bioavailability, and Therapeutic Potential.BioMed research international · 2025Review
- Interpretable machine learning for cardiovascular risk prediction: Insights from NHANES dietary and health data.PloS one · 2025Article
- Skin Carotenoids Are Related to Cognitive Abilities among Toddlers.The Journal of nutrition · 2024Article
- Comparing the Dietary Habits and the Food Choices Between Italian and Dominican Adult Populations: Focus on Fruit and Vegetable Intakes and Their Association with Skin Carotenoid Levels.Foods (Basel, Switzerland) · 2024Article
- Therapeutic effect of targeted antioxidant natural products.Discover nano · 2024Review
- Machine learning-driven risk assessment of coronary heart disease: Analysis of NHANES data from 1999 to 2018.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cardiovascular disease (CVD) has become a key global health issue. Serum carotenoids are associated with CVD, while their effects on different diseases remain unclear. Herein, the relationship between the concentration of serum carotenoid and the CVD risk was investigated using nationwide adult samples obtained from the USA. Materials and methods: Data of National Health and Nutrition Examination Survey (NHANES) in 2001-2006 were employed. The association of serum carotenoids (total, lycopene, β-carotene, α-carotene, lutein/zeaxanthin, and β-cryptoxanthin) with CVD was explored by using multivariate logistic, linear and weighted quantile sum (WQS) regression analyses. Eventually, data from 12,424 volunteers were analyzed for this study. Results: Multivariate model data showed that lutein/zeaxanthin, α-carotene, lycopene, and β-cryptoxanthin were negatively associated with the prevalence of CVD ( Conclusion: The concentration of serum carotenoids had negative correlation with the prevalence of CVD, with a more significant negative effect against heart attack and stroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.