Evidence map›Paper›PMID 37502678›Full record

ReviewBioactive materials2023

Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine.

Filipe V Ferreira, Alana G Souza, Rubina Ajdary, Lucas P de Souza, João H Lopes, Daniel S Correa, Gilberto Siqueira, Hernane S Barud, Derval Dos S Rosa, Luiz H C Mattoso and 1 more

Abstract readReview
In one paragraph

Review in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Filipe V FerreiraNanotechnology National Laboratory for Agriculture (LNNA), Embrapa Instrumentation - Rua XV de Novembro, 1452, São Carlos, SP, 13560-979, Brazil.
Alana G SouzaCenter for Engineering, Modeling, and Applied Social Sciences (CECS), Federal University of ABC (UFABC), Santo André, Brazil.
Rubina AjdaryDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, P. O. Box 16300, Aalto, Espoo, FIN-00076, Finland.
Lucas P de SouzaCollege of Engineering and Physical Sciences, Aston Institute of Materials Research, Aston University, Birmingham, UK.
João H LopesDepartment of Chemistry, Division of Fundamental Sciences (IEF), Technological Institute of Aeronautics (ITA), São Jose dos Campos, SP, Brazil.
Daniel S CorreaNanotechnology National Laboratory for Agriculture (LNNA), Embrapa Instrumentation - Rua XV de Novembro, 1452, São Carlos, SP, 13560-979, Brazil.
Gilberto SiqueiraLaboratory for Cellulose & Wood Materials, Empa - Swiss Federal Laboratories for Materials Science and Technology, Überlandstrasse 129, 8600, Dübendorf, Switzerland.
Hernane S BarudBiopolymers and Biomaterials Laboratory (BIOPOLMAT), University of Araraquara (UNIARA), Araraquara, 14801-340, São Paulo, Brazil.
Derval Dos S RosaCenter for Engineering, Modeling, and Applied Social Sciences (CECS), Federal University of ABC (UFABC), Santo André, Brazil.
Luiz H C MattosoNanotechnology National Laboratory for Agriculture (LNNA), Embrapa Instrumentation - Rua XV de Novembro, 1452, São Carlos, SP, 13560-979, Brazil.
Orlando J RojasDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, P. O. Box 16300, Aalto, Espoo, FIN-00076, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We review the recent progress that have led to the development of porous materials based on cellulose nanostructures found in plants and other resources. In light of the properties that emerge from the chemistry, shape and structural control, we discuss some of the most promising uses of a plant-based material, nanocellulose, in regenerative medicine. Following a brief discussion about the fundamental aspects of self-assembly of nanocellulose precursors, we review the key strategies needed for material synthesis and to adjust the architecture of the materials (using three-dimensional printing, freeze-casted porous materials, and electrospinning) according to their uses in tissue engineering, artificial organs, controlled drug delivery and wound healing systems, among others. For this purpose, we map the structure-property-function relationships of nanocellulose-based porous materials and examine the course of actions that are required to translate innovation from the laboratory to industry. Such efforts require attention to regulatory aspects and market pull. Finally, the key challenges and opportunities in this nascent field are critically reviewed.

Indexed as

BiomaterialCellulose nanocrystalsCellulose nanofibrilsGreen nanomaterialsRegenerative medicineSustainable materials

Identifiers

PMID37502678
PMCPMC10368849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.