Evidence map›Paper›PMID 37502470›Full record

ArticleCureus2023

Long-Term Outcomes of Transanal Irrigation for Bowel Dysfunction.

Panagiotis Tamvakeras, Clare Horrobin, Jessica Chang, Mark Chapman

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06569446 (Understanding the Barriers to Rectal Irrigation in Patients With Defaecatory Dysfunction), which is not on this map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06569446 unknown statusnot on this mapstarted 2024, after this paper: background citation

Understanding the Barriers to Rectal Irrigation in Patients With Defaecatory Dysfunction

TypeobservationalSponsorGuy's and St Thomas' NHS Foundation TrustRan2024 to 2025Enrolled34ConditionsDefecation Disorder, Constipation - Functional, Constipation by Outlet Obstruction, Faecal IncontinenceArmsThere is no intervention. This a qualitative study to explore barriers to rectal irrigation
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Guideline
  2. Transanal irrigation: Bridging the gap in treatment for chronic constipation and/or faecal incontinence-A systematic review and management guidance.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Pooled it
  3. Pooled it
  4. Transanal irrigation in clinical practice: a scoping review.International journal of colorectal disease · 2026
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Panagiotis TamvakerasColorectal Surgery, University Hospitals Birmingham NHS Foundation Trust, The Royal Town of Sutton Coldfield, GBR.
Clare HorrobinLower GI Physiology, University Hospitals Birmingham NHS Foundation Trust, The Royal Town of Sutton Coldfield, GBR.
Jessica ChangColorectal Surgery, University Hospitals Birmingham NHS Foundation Trust, The Royal Town of Sutton Coldfield, GBR.
Mark ChapmanColorectal Surgery, University Hospitals Birmingham NHS Foundation Trust, The Royal Town of Sutton Coldfield, GBR.
University Hospitals Birmingham NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTransanal irrigation (TAI) improves bowel function and quality of life in patients with neurogenic bowel disease compared to conservative bowel care. Its use has been extended to a range of defecatory disorders. However, data on long-term benefits and compliance are lacking. We aim to evaluate the long-term efficacy of TAI by examining compliance and patient outcomes over a five-year period.

methodsThis study is a five-year retrospective review of patients practising TAI in a district general hospital. Patient demographics, indications, long-term compliance, adverse events, and patient-reported Qufora bowel symptom bother scores were analysed.

resultsA cohort of 18 patients had a median age of 61 (range 23-91) and were predominantly female (83.5%). The reasons for bowel dysfunction were diverse: low anterior resection syndrome, neurogenic bowel, congenital anorectal malformations, obstructed defecation, and functional disorders. Predominant symptoms were constipation (9), faecal incontinence (7), and mixed (2). Both high-volume (catheter and cone) and low-volume (mini cone) irrigation devices were used. Fourteen patients continued regular irrigation at a median follow-up of 27.7 months (range 5.1-72.3), while four had discontinued at a median follow-up of 4.8 months. The reasons for discontinuation were inadequate rectal evacuation and spontaneous improvement of symptoms. In the compliant group, there was a significant improvement in bowel symptom scores (p=0.003). No major adverse events, such as significant rectal bleeding or perforation, were noted.

conclusionIn this small cohort, TAI was safe and effective for long-term use; however, a fifth of patients discontinued treatment. Further work needs to be done to identify those patients who will benefit from TAI.

Indexed as

bowel dysfunctionpelvic floor disorderpelvic floor dysfunctionrectal irrigationtransanal irrigation

Identifiers

PMID37502470
PMCPMC10371390
OpenAlexW4385319813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.