Evidence map›Paper›PMID 37502335›Full record

ArticleChemical science2023

A highly enantioselective intramolecular 1,3-dipolar cycloaddition yields novel pseudo-natural product inhibitors of the Hedgehog signalling pathway.

Jie Liu, Ruirui Zhang, Shubhadip Mallick, Sohan Patil, Chantal Wientjens, Jana Flegel, Anna Krupp, Carsten Strohmann, Corentin Grassin, Christian Merten and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Jie LiuDepartment of Chemical Biology, Max Planck Institute of Molecular Physiology Otto-Hahn-Street 11 44227 Dortmund Germany Herbert.waldmann@mpi-dortmund.mpg.de.ORCID https://orcid.org/0000-0002-9455-325X
Ruirui ZhangDepartment of Chemical Biology, Max Planck Institute of Molecular Physiology Otto-Hahn-Street 11 44227 Dortmund Germany Herbert.waldmann@mpi-dortmund.mpg.de.ORCID https://orcid.org/0000-0001-9342-2613
Shubhadip MallickDepartment of Chemical Biology, Max Planck Institute of Molecular Physiology Otto-Hahn-Street 11 44227 Dortmund Germany Herbert.waldmann@mpi-dortmund.mpg.de.
Sohan PatilDepartment of Chemical Biology, Max Planck Institute of Molecular Physiology Otto-Hahn-Street 11 44227 Dortmund Germany Herbert.waldmann@mpi-dortmund.mpg.de.
Chantal WientjensFaculty of Chemistry, Chemical Biology, Technical University Dortmund Otto-Hahn-Street 6 44221 Dortmund Germany.
Jana FlegelDepartment of Chemical Biology, Max Planck Institute of Molecular Physiology Otto-Hahn-Street 11 44227 Dortmund Germany Herbert.waldmann@mpi-dortmund.mpg.de.
Anna KruppFaculty of Chemistry, Inorganic Chemistry, Technical University Dortmund Otto-Hahn-Street 6 44221 Dortmund Germany.
Carsten StrohmannFaculty of Chemistry, Inorganic Chemistry, Technical University Dortmund Otto-Hahn-Street 6 44221 Dortmund Germany.
Corentin GrassinFaculty of Chemistry and Biochemistry, Organic Chemistry II, Ruhr University Bochum University-Street 150 44801 Bochum Germany.ORCID https://orcid.org/0000-0002-7605-0878
Christian MertenFaculty of Chemistry and Biochemistry, Organic Chemistry II, Ruhr University Bochum University-Street 150 44801 Bochum Germany.ORCID https://orcid.org/0000-0002-4106-1905
Axel PahlDepartment of Chemical Biology, Max Planck Institute of Molecular Physiology Otto-Hahn-Street 11 44227 Dortmund Germany Herbert.waldmann@mpi-dortmund.mpg.de.
Michael GrigalunasDepartment of Chemical Biology, Max Planck Institute of Molecular Physiology Otto-Hahn-Street 11 44227 Dortmund Germany Herbert.waldmann@mpi-dortmund.mpg.de.ORCID https://orcid.org/0000-0003-0419-8168
Herbert WaldmannDepartment of Chemical Biology, Max Planck Institute of Molecular Physiology Otto-Hahn-Street 11 44227 Dortmund Germany Herbert.waldmann@mpi-dortmund.mpg.de.ORCID https://orcid.org/0000-0002-9606-7247
Max Planck Institute of Molecular Physiology · DETU Dortmund University · DERuhr University Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID37502335
PMCPMC10370549
OpenAlexW4381547510

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.