Evidence map›Paper›PMID 37502251›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2023

Quantifying the Implementation and Cost of a Multisite Antibiotic Stewardship Intervention for Asymptomatic Bacteriuria.

Eva Amenta, Larissa Grigoryan, Suja S Rajan, David Ramsey, Jennifer R Kramer, Annette Walder, Andrew Chou, John N Van, Sarah L Krein, Sylvia Hysong and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04922320 (Effect of Patient Priorities Care Implementation in Older Veterans With Multiple Chronic Conditions), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04922320 nacompletednot on this map

Effect of Patient Priorities Care Implementation in Older Veterans With Multiple Chronic Conditions

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2022 to 2025Enrolled420ConditionsMultiple Chronic Conditions, Decision Making, SharedArmsPatient Priorities Care, Usual Care
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Eva AmentaMichael E. DeBakey Veteran Affairs Medical Center, Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Houston, TX, USA.ORCID https://orcid.org/0000-0002-9224-7056
Larissa GrigoryanMichael E. DeBakey Veteran Affairs Medical Center, Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Houston, TX, USA.
Suja S RajanUTHealth Science Center, Institute for Stroke and Cerebral Vascular Disease, Houston, TX, USA.
David RamseyMichael E. DeBakey Veteran Affairs Medical Center, Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Houston, TX, USA.
Jennifer R KramerMichael E. DeBakey Veteran Affairs Medical Center, Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Houston, TX, USA.
Annette WalderMichael E. DeBakey Veteran Affairs Medical Center, Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Houston, TX, USA.ORCID https://orcid.org/0000-0003-4799-6039
Andrew ChouMichael E. DeBakey Veteran Affairs Medical Center, Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Houston, TX, USA.ORCID https://orcid.org/0000-0002-2520-6959
John N VanMichael E. DeBakey Veteran Affairs Medical Center, Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Houston, TX, USA.
Sarah L KreinCenter for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Sylvia HysongMichael E. DeBakey Veteran Affairs Medical Center, Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Houston, TX, USA.ORCID https://orcid.org/0000-0002-9063-5207
Aanand D NaikMichael E. DeBakey Veteran Affairs Medical Center, Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Houston, TX, USA.ORCID https://orcid.org/0000-0001-6936-7984
Barbara W TrautnerMichael E. DeBakey Veteran Affairs Medical Center, Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Houston, TX, USA.ORCID https://orcid.org/0000-0001-7986-9099
Michael E. DeBakey VA Medical Center · USThe University of Texas Health Science Center at Houston · USUniversity of Michigan · US

Funding

Less is More: Improving Antimicrobial Stewardship for Asymptomatic BacteriuriaI01HX002171 · VA · MICHAEL E DEBAKEY VA MEDICAL CENTER · PI TRAUTNER, BARBARA WELLS · 2018 to 2021
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Research Career Scientist AwardIK6HX003399 · VA · VETERANS HEALTH ADMINISTRATION · PI KREIN, SARAH · 2023 to 2025
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HSRD VA I01 HX002171HSRD VA IK6 HX003399
6 · The paper itself

Abstract

Objective: The intensity of an antibiotic stewardship intervention to achieve clinical impact is not known. We conducted a multisite dissemination project of an intervention to reduce treatment of asymptomatic bacteriuria (ASB) and studied: (1) the association between implementation metrics and clinical outcomes and (2) the cost of implementation. Design/Setting/Participants: A central site facilitated a multimodality intervention to decrease unnecessary urine cultures and antibiotic treatment in patients with ASB at 4 Veterans Affairs medical centers. Methods: The intervention consisted of a decision support aid algorithm and interactive teaching cases that provided in the moment audit and feedback on how to manage ASB. Implementation outcomes included minutes spent in intervention delivery, number of healthcare professionals reached, and number of sessions delivered. Clinical outcomes included days of antibiotic therapy (DOT), length of antibiotic therapy (LOT), and number of urine cultures ordered per 1000 bed days. Personnel reported weekly time logs. Results: Minutes spent in intervention delivery were inversely correlated with two clinical outcomes, DOT ( Conclusions: The amount of time local teams spent in delivery of an antibiotic stewardship intervention was correlated with the desired decrease in antibiotic use. Implementing this successful antibiotic stewardship intervention required minimal time.

Identifiers

PMID37502251
PMCPMC10369447
OpenAlexW4382775673

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.