Evidence map›Paper›PMID 37502246›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2023

Risk for primary cephalosporin resistance in Gram-negative bacteremia.

Princy John, Sona Shahbazian, William D Lainhart, Justin Hayes, Brian Mochon, David E Nix

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Princy JohnBanner Health.
Sona ShahbazianCollege of Medicine, University of Arizona, Tucson, Arizona.ORCID https://orcid.org/0000-0003-1688-5010
William D LainhartDepartment of Pathology & Laboratory Medicine, University of Arizona, Tucson, Arizona.ORCID https://orcid.org/0000-0002-9372-6737
Justin HayesCollege of Medicine, University of Arizona, Tucson, Arizona.ORCID https://orcid.org/0000-0003-4360-961X
Brian MochonDepartment of Pathology & Laboratory Medicine, University of Arizona, Tucson, Arizona.ORCID https://orcid.org/0000-0003-4765-4311
David E NixCollege of Medicine, University of Arizona, Tucson, Arizona.ORCID https://orcid.org/0000-0002-9440-465X
University of Arizona · USBanner Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to examine the clinical risk factors for cephalosporin resistance in patients with Gram-negative bacteremia caused by Methods: This retrospective cohort study included 400 adults with Gram-negative bacteremia. The goal was to review 100 cases involving each species and approximately half resistant and half susceptible to first-line cephalosporins, ceftriaxone (EC or KP), or cefepime (ENC or PS). Logistic regression was used to identify factors predictive of resistance. Results: A total of 378 cases of Gram-negative bacteremia were included in the analysis. Multivariate analysis identified significant risk factors for resistance, including admission from a chronic care hospital, skilled nursing facility, or having a history of infection within the prior 6 months (OR 3.00, Conclusions: Patients without the identified risk factors should be strongly considered for receiving ceftriaxone or cefepime rather than carbapenems and newer broad-spectrum agents.

Identifiers

PMID37502246
PMCPMC10369432
OpenAlexW4383739282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.