Evidence map›Paper›PMID 37501919›Full record

Article3 Biotech2023

A novel monospecific tetravalent IgG1-(scFv)

Zhang-Zhao Gao, Jing-Yu Jiao, Ya-Qiong Zhou, Jian Qi, Shan-Shan Zhu, Jing-Ya Xu, Lei Nie, Hai-Bin Wang

Open access · greenAbstract read
In one paragraph

Article in 3 Biotech, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhang-Zhao GaoBioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.ORCID 0000-0001-9516-6377
Jing-Yu JiaoBioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Ya-Qiong ZhouBioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Jian QiBioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Shan-Shan ZhuBioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Jing-Ya XuBioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Lei NieBioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Hai-Bin WangBioRay Biopharmaceutical Co., Ltd., Taizhou, 318000 Zhejiang China.
Jiangsu T-mab BioPharma (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutralizing monoclonal antibodies (nMABs) have been proved to be effective therapeutics in treating coronavirus disease (COVID-19). To enhance the potency of nMAB 553-15, we generated a novel monospecific tetravalent IgG1-(scFv)

Indexed as

COVID-19Fc-mediated effector functionsNeutralizingTetravalent antibody

Identifiers

PMID37501919
PMCPMC10368608
OpenAlexW4385260544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.