Evidence map›Paper›PMID 37501910›Full record

ArticleBrain communications2023

Physiological alterations of pineal recess crowding in symptomatic non-hydrocephalic pineal cysts.

Per Kristian Eide, Erika Kristina Lindstrøm, Are Hugo Pripp, Lars Magnus Valnes, Geir Ringstad

Open access · goldAbstract readComment
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Per Kristian EideInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, N-0316 Oslo, Norway.ORCID https://orcid.org/0000-0001-6881-9280
Erika Kristina LindstrømInstitute for Cancer Genetics and Informatics, Oslo University Hospital, N-0424 Oslo, Norway.
Are Hugo PrippOslo Centre of Biostatistics and Epidemiology, Research Support Services, Oslo University Hospital, N-0424 Oslo, Norway.
Lars Magnus ValnesDepartment of Neurosurgery, Oslo University Hospital-Rikshospitalet, N-0424 Oslo, Norway.
Geir RingstadDepartment of Radiology, Oslo University Hospital- Rikshospitalet, N-0424 Oslo, Norway.
Oslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pineal cysts are prevalent in the population. Due to more widespread use of magnetic resonance imaging, an increasing number of symptomatic patients with non-hydrocephalic pineal cysts are referred to neurologists and neurosurgeons. Currently, there is no generally accepted theoretical framework for linking symptoms to a pineal cyst. We have previously suggested that cyst-induced crowding of the pineal recess may affect venous runoff from the deep cerebral veins crossing the cyst. However, evidence underpinning this hypothesis is sparse. In the present study, we asked whether crowding of the pineal recess without imaging signs of hydrocephalus may be accompanied with alterations in blood flow of the internal cerebral veins, cerebrospinal fluid flow in the Sylvian aqueduct and cerebrospinal fluid-mediated tracer clearance from the brain along extravascular pathways (referred to as glymphatic function). This prospective, observational study included symptomatic individuals with non-hydrocephalic pineal cysts who underwent a standardized magnetic resonance imaging protocol (

Indexed as

cerebrospinal fluidglymphatic functionmagnetic resonance imagingpathophysiologysymptomatic pineal cysts

Identifiers

PMID37501910
PMCPMC10371044
OpenAlexW4327813416

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.