Evidence map›Paper›PMID 37501678›Full record

ArticleRegenerative biomaterials2023

Medium chain length polyhydroxyalkanoates as potential matrix materials for peripheral nerve regeneration.

Rinat Nigmatullin, Caroline S Taylor, Pooja Basnett, Barbara Lukasiewicz, Alexandra Paxinou, Lorena R Lizarraga-Valderrama, John W Haycock, Ipsita Roy

Open access · goldAbstract read
In one paragraph

Article in Regenerative biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Rinat NigmatullinHigher Steaks Ltd., 25 Cambridge Science Park Rd, Milton, Cambridge CB4 0FW, UK.ORCID https://orcid.org/0000-0003-3517-1208
Caroline S TaylorDepartment of Materials Science & and Engineering, The University of Sheffield, Sheffield S3 7HQ, UK.ORCID https://orcid.org/0000-0002-9042-9913
Pooja BasnettSchool of Life Sciences, College of Liberal Arts and Sciences, University of Westminster, London W1B 2HW, UK.ORCID https://orcid.org/0000-0002-1478-6097
Barbara LukasiewiczSchool of Life Sciences, College of Liberal Arts and Sciences, University of Westminster, London W1B 2HW, UK.
Alexandra PaxinouSchool of Life Sciences, College of Liberal Arts and Sciences, University of Westminster, London W1B 2HW, UK.
Lorena R Lizarraga-ValderramaSchool of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK.ORCID https://orcid.org/0000-0002-3200-5733
John W HaycockDepartment of Materials Science & and Engineering, The University of Sheffield, Sheffield S3 7HQ, UK.ORCID https://orcid.org/0000-0002-3950-3583
Ipsita RoyDepartment of Materials Science & and Engineering, The University of Sheffield, Sheffield S3 7HQ, UK.ORCID https://orcid.org/0000-0001-5602-1714
University of Sheffield · GBUniversity of Westminster · GBFoundation for Research and Technology Hellas · GRUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyhydroxyalkanoates are natural, biodegradable, thermoplastic and sustainable polymers with a huge potential in fabrication of bioresorbable implantable devices for tissue engineering. We describe a comparative evaluation of three medium chain length polyhydroxyalkanoates (mcl-PHAs), namely poly(3-hydroxyoctanoate), poly(3-hydroxyoctanoate-co-3-hydoxydecanoate) and poly(3-hydroxyoctanoate-co-3-hydroxydecanoate-co-3-hydroxydodecanoate), one short chain length polyhydroxyalkanoate, poly(3-hydroxybutyrate), P(3HB) and synthetic aliphatic polyesters (polycaprolactone and polylactide) with a specific focus on nerve regeneration, due to mechanical properties of mcl-PHAs closely matching nerve tissues.

Indexed as

biomaterialsmcl-polyhydroxyalkanoatesnerve regenerationNG108-15peripheral nerve injurySchwann cells

Identifiers

PMID37501678
PMCPMC10369215
OpenAlexW4384920730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.