Evidence map›Paper›PMID 37501136›Full record

ReviewBMC pulmonary medicine2023

Retrospective analysis of pulmonary cryptococcosis and extrapulmonary cryptococcosis in a chinese tertiary hospital.

Jiejun Shi, Jianhua Chen, Liqing Hu, Ada Hoi Yan Ma, Haoxuan Hu, Chuwen Wang, Jiajia Huang, Qifa Song, Guoqing Qian

Open access · goldAbstract readReview
In one paragraph

Review in BMC pulmonary medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Clinicopathological Analysis of 60 Cases of Pulmonary Cryptococcosis.International journal of general medicine · 2025
    Article
  8. Article
  9. Comparison of performances of laboratory methods in diagnosing pulmonary cryptococcosis in 1508 patients having lung biopsy tissues collected: a 6-year retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jiejun ShiDepartment of Infectious Diseases, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang Province, China. 804175955@qq.com.ORCID http://orcid.org/0000-0003-0911-2773
Jianhua ChenDepartment of Radiology, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang Province, China.ORCID http://orcid.org/0000-0002-4214-557X
Liqing HuDepartment of Clinical Laboratory, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
Ada Hoi Yan MaNottingham University Business School, University of Nottingham Ningbo China, Ningbo, Zhejiang Province, China.
Haoxuan HuDepartment of Internal Medicine, Fenghua District Hospital, Ningbo, Zhejiang Province, China.
Chuwen WangSchool of Medicine, Ningbo University, Ningbo, Zhejiang, China.
Jiajia HuangSchool of Medicine, Ningbo University, Ningbo, Zhejiang, China.
Qifa SongMedical Data Research Center, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang Province, China.
Guoqing QianDepartment of Infectious Diseases, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang Province, China.ORCID http://orcid.org/0000-0003-2427-8042
Ningbo University · CNGuhua Hospital · CNUniversity of Nottingham Ningbo China · CN

Funding

Natural Science Foundation of Ningbo 202003N4019
6 · The paper itself

Abstract

Cryptococcosis is an invasive fungal disease with increased morbidity in China over the past two decades. Cryptococci can infect immunocompromised hosts as well as immunocompetent ones. In this study, we reviewed data of 71 inpatients with cryptococcosis at Ningbo First Hospital from May 2010 to May 2020 and compared the clinical profiles of pulmonary cryptococcosis (PC) and extrapulmonary cryptococcosis (EPC). Of 71 patients (38 males, 33 females), 70 were non-HIV. The annual inpatient population increased dramatically, especially in the PC group. PC was confirmed in 77.46% (55/71) of cases by pathology. The rest were EPC including intracranial infection (15.49%, 11/71) and cryptococcemia (7.04%, 5/71). Compared with PC, a larger proportion of EPC patients were found to have immunocompromised conditions judged by predisposing factors (p < 0.01), or detectable humoral or cellular immunodeficiency. Fever and headache were more common in EPC patients (p < 0.001). Patients with EPC had lower serum sodium level (p = 0.041), lower monocyte counts (p = 0.025) and higher C-reactive protein (p = 0.012). In our study, the sensitivity of cryptococcus antigen detection for EPC was 100% regardless of sample type, while serum lateral flow assay (LFA) tested negative in 25% (5/20) of PC. Immunocompromised hosts are more likely to suffer from EPC than PC.

Indexed as

CryptococcosisEast Asian PeopleAntigens, FungalChinaFemaleHumansMaleRetrospective StudiesTertiary Care CentersAntigens, FungalCryptococcal antigen testExtrapulmonary cryptococcosisImmune statePulmonary cryptococcosis

Identifiers

PMID37501136
PMCPMC10375642
OpenAlexW4385329983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.