Evidence map›Paper›PMID 37501110›Full record

ArticleBMC musculoskeletal disorders2023

Fatty infiltration of the cervical multifidus musculature and its clinical correlation to cervical spondylosis.

Zhifei Li, Qinqiu Liang, He Li, Xiaocheng Lin, Jiwen Meng, Daishui Yang, Chengwei Li, Yuanyao Liang, Yin Yang, Yuanfang Lin and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Zhifei LiDepartment of Spine Surgery, The First Affiliated Hospital of Guangxi University of Chinese medicine, Nanning, 530023, Guangxi, China.
Qinqiu LiangGuangxi University of Chinese medicine, Nanning, 530001, Guangxi, China.
He LiDepartment of Spine Manipulation, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, 518033, Guangdong, China.
Xiaocheng LinMacalester College, Saint Paul, MN, 55105, USA.
Jiwen MengGuangxi University of Chinese medicine, Nanning, 530001, Guangxi, China.
Daishui YangDepartment of Orthopaedic, Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.
Chengwei LiGuangxi University of Chinese medicine, Nanning, 530001, Guangxi, China.
Yuanyao LiangGuangxi University of Chinese medicine, Nanning, 530001, Guangxi, China.
Yin YangGuangxi University of Chinese medicine, Nanning, 530001, Guangxi, China.
Yuanfang LinDepartment of Spine Manipulation, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, 518033, Guangdong, China. 13602577968@139.com.
Ziyang LiangDepartment of Spine Manipulation, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, 518033, Guangdong, China. young8637@sina.com.
Guangxi University · CNGuangzhou University of Chinese Medicine · CNCentral South University · CNMacalester College · USSecond Xiangya Hospital of Central South University · CN

Funding

Fellowship of China Postdoctoral Science Foundation 2022M723569Natural Science Foundation of Changsha City kq2202390Natural Science Foundation of Guangxi Zhuang Autonomous Region 2023GXNSFAA026101Natural Science Foundation of Hunan Province 2022JJ40696Scientific Research Project of Traditional Chinese Medicine Bureau of Hunan Province B2023011Shenzhen Science and Technology Innovation Program JCYJ20210324111212035
6 · The paper itself

Abstract

purposeFat infiltration (FI) of the deep neck extensor muscles has been shown to be associated with poor outcomes in cervical injury, mechanical neck pain, and axial symptoms after cervical spine surgery. However, information is scarce on the severity of FI in cervical extensors associated with different clinical syndromes in patients with cervical spondylosis.

objectiveTo investigate the relationship between the severity of FI in the cervical multifidus musculature and its clinical correlates in the syndromes and sagittal alignment of patients with cervical spondylosis.

methodsThis study was conducted as a retrospective study of twenty-eight healthy volunteers (HV) together with sixty-six patients who underwent cervical radiculopathy (CR), degenerative myelopathy (DM), and axial joint pain (AJP) from January 2020 to March 2022. MRI was used to measure the fat cross-sectional area (FCSA), functional muscle cross-sectional area (FMCSA), total muscle cross-sectional area (TMCSA), FI ratio of the cervical multifidus musculature at each cervical level from the C3 to C6 segments and the cervical lordosis angle in the included subjects.

resultsThe difference in the FCSA and FI ratio in patient groups with cervical spondylosis was significantly greater than that of the HV group (P < 0.05), and the Cobb angle of the DM group, AJP group and HV group was significantly greater than that of the CR group (P < 0.05). The FI ratio comparison showed no significant difference by sex, and the comparison of FCSA, FMCSA, TMCSA and FI ratio showed no significant difference by age range from 35 to 69 in the included subjects. The FCSA and TMCSA in patients with cervical spondylosis were positively related to the Cobb angle (r

conclusionCompared with healthy subjects, a more severe degree of FI in the multifidus musculature and sagittal imbalance were found in patients with cervical spondylosis. These two imaging features are considered to be important concomitant phenomena of cervical spondylosis, and the more severe FI is, the worse the sagittal imbalance. However, each syndrome had no obvious difference in FI in the multifidus musculature.

Indexed as

RadiculopathySpondylosisCervical VertebraeHumansParaspinal MusclesRetrospective StudiesSyndromeCervical multifidusCorrelation analysisCross-sectional areaFat infiltrationRadiological measurement

Identifiers

PMID37501110
PMCPMC10373323
OpenAlexW4385308543

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.