Evidence map›Paper›PMID 37501064›Full record

ArticleTrials2023

Analysis of the relationship between EEG burst suppression and poor prognosis in children under general anaesthesia: study protocol for a prospective, observational, single-centre study.

Qian Xu, Jianmin Zhang, Zhengzheng Gao, Shanshan Li, Gan Li

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qian XuDepartment of Anesthesiology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, No.56, South Lishi Road, Beijing, 100045, China.
Jianmin ZhangDepartment of Anesthesiology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, No.56, South Lishi Road, Beijing, 100045, China. zhangjianmin@bch.com.cn.
Zhengzheng GaoDepartment of Anesthesiology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, No.56, South Lishi Road, Beijing, 100045, China.
Shanshan LiDepartment of Anesthesiology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, No.56, South Lishi Road, Beijing, 100045, China.
Gan LiDepartment of Anesthesiology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, No.56, South Lishi Road, Beijing, 100045, China.
Beijing Children’s Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmergence delirium (ED) in children refers to the immediate postoperative period when children experience decreased perception of their surroundings, accompanied by disorientation and altered perception. Burst suppression (BS) is recognised as periods longer than 0.50 s during which the EEG does not exceed approximately + 5.0 mV, which is an electroencephalographic state associated with profound inactivation of the brain. Our primary objective was to determine the association between BS on electroencephalogram (EEG) under general anaesthesia with postoperative wake-up delirium and multiple adverse outcomes, such as prolonged awakening and extubation.

methodsIn this prospective, observational cohort study at Beijing Children's Hospital, Capital Medical University, Beijing, China, children aged 6 months to 9 years who underwent surgery under general anaesthesia and underwent EEG monitoring between January 2022 and January 2023 were included. Patients' prefrontal EEGs were recorded intraoperatively as well as analysed for the occurrence and duration of BS and scored postoperatively for delirium by the PAED scale, with a score of no less than 10 considered as having developed wake-up delirium. DISCUSSION: This study identified a relationship between EEG BS and postoperative awakening delirium under general anaesthesia in children and provides a novel preventive strategy for postoperative awakening delirium and multiple adverse outcomes in paediatric patients.

trial registrationChinese Clinical Trial Registry, ChiCTR2200055256. Registered on January 5, 2022.

Indexed as

Emergence DeliriumAnesthesia, GeneralAnesthesia Recovery PeriodChildElectroencephalographyHumansObservational Studies as TopicPrognosisProspective StudiesBurst suppressionEEGEmergence deliriumGeneral anaesthesia

Identifiers

PMID37501064
PMCPMC10375778
OpenAlexW4385296776

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.