ArticleMolecular psychiatry2023
Association between non-medical cannabis legalization and emergency department visits for cannabis-induced psychosis.
Article in Molecular psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed.
- An etiological approach to psychosis: potential benefits for treatment, research and prevention.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Emergency department use by individuals with and without psychosis after state-level cannabis legalization and commercialization.Nature. Mental health · 2026Article
- Public health impacts of legalizing recreational cannabis use in Canada and the US.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Centering Individuals With Mental Illness as an At-Risk Group in the Era of Cannabis Legalization and Commercialization.Clinical therapeutics · 2026Article
- Cannabis, psychosis, and violence: case reports and comprehensive evidence review.Frontiers in psychiatry · 2026Article
- Trends in cannabis-attributable hospitalizations and emergency department visits: data from the Canadian Substance Use Costs and Harms Study (2007-2020).Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025Article
- Cannabis Use and Misuse Following Recreational Cannabis Legalization.JAMA network open · 2025Article
- Changes in Incident Schizophrenia Diagnoses Associated With Cannabis Use Disorder After Cannabis Legalization.JAMA network open · 2025Article
- Exploring the impact of drug decriminalization and legalization policies on mental health outcomes: A scoping review.PLOS mental health · 2025Article
- "Like the Wild West": Health care provider perspectives on impacts of recreational cannabis legalization on patients and providers at a tertiary psychiatric hospital in Ontario, Canada.Journal of substance use and addiction treatment · 2024Article
- Reply to Zhou et al's "Refining Psychosis Research: Insights on Cannabis Use and Data Accuracy".Schizophrenia bulletin · 2024Article
- Changes in cannabis involvement in emergency department visits for anxiety disorders after cannabis legalization: a repeated cross-sectional study.Lancet regional health. Americas · 2024Article
- Neuromodulation for Cannabis Use: A Scoping Review.Brain sciences · 2024Article
- The association between physical availability of cannabis retail outlets and frequent cannabis use and related health harms: a systematic review.Lancet regional health. Americas · 2024Review
- Development of an anxiety disorder following an emergency department visit due to cannabis use: a population-based cohort study.EClinicalMedicine · 2024Article
- Article
- Outcomes associated with nonmedical cannabis legalization policy in Canada: taking stock at the 5-year mark.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Article
- Changes in Cannabis-Attributable Hospitalizations Following Nonmedical Cannabis Legalization in Canada.JAMA network open · 2023Article
- Cannabis and Psychosis: Weeding Out Fact from Fiction.Missouri medicineArticle
- TheJournal of psychiatry & neuroscience : JPNArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
A major public health concern of cannabis legalization is that it may result in an increase in psychotic disorders. We examined changes in emergency department (ED) visits for cannabis-induced psychosis following the legalization and subsequent commercialization (removal of restrictions on retail stores and product types) of non-medical cannabis in Ontario, Canada (population of 14.3 million). We used health administrative data containing the cause of all ED visits to examine changes over three periods; 1) pre-legalization (January 2014-September 2018); 2) legalization with restrictions (October 2018 - February 2020); and 3) commercialization (March 2020 - September 2021). We considered subgroups stratified by age and sex and examined cocaine- and methamphetamine-induced psychosis ED visits as controls. During our study, there were 6300 ED visits for cannabis-induced psychosis. The restricted legalization period was not associated with changes in rates of ED visits for cannabis-induced psychosis relative to pre-legalization. The commercialization period was associated with an immediate increase in rates of ED visits for cannabis-induced psychosis (IRR 1.30, 95% CI 1.02-1.66) and no gradual monthly change; immediate increases were seen only for youth above (IRR 1.63, 1.27-2.08, ages 19-24) but not below (IRR 0.73 95%CI 0.42-1.28 ages, 15-18) the legal age of purchase, and similar for men and women. Commercialization was not associated with changes in rates of ED visits for cocaine- or methamphetamine-induced psychosis. This suggests that legalization with store and product restrictions does not increase ED visits for cannabis-induced psychosis. In contrast, cannabis commercialization may increase cannabis-induced psychosis presentations highlighting the importance of preventive measures in regions considering legalization.
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Registered trials
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