Evidence map›Paper›PMID 37500688›Full record

ArticleScientific reports2023

Cool executive functions and their association with body mass & fatness and the FTO gene in school-aged children.

Paula Szcześniewska, Ewa Bryl, Agata Dutkiewicz, Aneta R Borkowska, Karolina Bilska, Elżbieta Paszyńska, Agnieszka Słopień, Monika Dmitrzak-Węglarz, Tomasz Hanć

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Paula SzcześniewskaInstitute of Biology and Human Evolution, Faculty of Biology, Adam Mickiewicz University, 61-614, Poznan, Poland. paula.mamrot@amu.edu.pl.
Ewa BrylInstitute of Biology and Human Evolution, Faculty of Biology, Adam Mickiewicz University, 61-614, Poznan, Poland.
Agata DutkiewiczDepartment of Child and Adolescent Psychiatry, Poznan University of Medical Sciences, 60-572, Poznan, Poland.
Aneta R BorkowskaFaculty of Education and Psychology, Maria Curie-Sklodowska University, 20-400, Lublin, Poland.
Karolina BilskaDepartment of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, 61-701, Poznan, Poland.
Elżbieta PaszyńskaDepartment of Integrated Dentistry, Poznan University of Medical Sciences, 60-812, Poznan, Poland.
Agnieszka SłopieńDepartment of Child and Adolescent Psychiatry, Poznan University of Medical Sciences, 60-572, Poznan, Poland.
Monika Dmitrzak-WęglarzDepartment of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, 61-701, Poznan, Poland.
Tomasz HanćInstitute of Biology and Human Evolution, Faculty of Biology, Adam Mickiewicz University, 61-614, Poznan, Poland. tomekh@amu.edu.pl.
Poznan University of Medical Sciences · PLAdam Mickiewicz University in Poznań · PLMaria Curie-Skłodowska University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The FTO gene rs9936909 polymorphism is one of the well-documented single nucleotide polymorphisms in the context of increased risk of obesity, including in children. Few studies have tested the association of the FTO gene with cognitive functions. Deficits of "cool" executive functions (EFs) are considered a potential risk factor for excessive weight. The aims of our study were to investigate whether cool EFs are associated with the Body Mass Index, the Fat Mass Index and the risk of excess body mass and overfatness in neurotypically school-aged children, and whether the FTO gene polymorphism is involved in development of this possible association. The sample consisted of 553 children aged 6-12 years old. A body composition analysis, a neuropsychological assessment of EFs, and FTO polymorphism genotyping were performed in the children studied. The study found a significant association of an interference effect in theStroop Color-Word Interference Task and the risk of excessive body fatness, but not excessive body mass. There were no explicit associations between the FTO genotype and EFs deficits. Environmental factors, and particularly low maternal education, appeared to be the strongest contributors to the increased risk of obesity.

Indexed as

AdiposityAlpha-Ketoglutarate-Dependent Dioxygenase FTOExecutive FunctionBody Mass IndexChildGenetic Predisposition to DiseaseGenotypeHumansPediatric ObesityPolymorphism, Single NucleotideAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, human

Identifiers

PMID37500688
PMCPMC10374888
OpenAlexW4385330204

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.