Evidence map›Paper›PMID 37500508›Full record

ArticleTobacco control2025

Still 'Cool': tobacco industry responds to state-wide menthol ban with synthetic coolants.

Michelle K Page, Emily E Paul, Noel J Leigh, Leah R Meza, Artur Galimov, Steve Sussman, Adam Leventhal, Richard J O'Connor, Maciej L Goniewicz

Open access · hybridAbstract read
In one paragraph

Article in Tobacco control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. The Impact of Menthol Cigarette Bans: A Systematic Review and Meta-Analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Pooled it
  2. Trial
  3. Synthetic cooling agents enhance nicotine reinforcement and mesolimbic dopamine signaling.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Article
  5. Mapping the flavoring landscape: a comparative analysis of tobacco and related products.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Commentary Paper on Cooling Flavors in Cigarette and Non-Cigarette Tobacco Products.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  12. Article
  13. Article
  14. Comparison of Nicotine and Selected Flavoring Contents Between Tobacco-Free and Tobacco-Containing Oral Pouches.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  15. Artificial Sweeteners in US-Marketed Oral Nicotine Pouch Products: Correlation With Nicotine Contents and Effects on Product Preference.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Michelle K PageDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA michelle.page@roswellpark.org.ORCID 0000-0002-5962-8586
Emily E PaulDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Noel J LeighDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.ORCID 0000-0002-6850-9634
Leah R MezaDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID 0000-0003-1001-3350
Artur GalimovDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID 0000-0002-9718-439X
Steve SussmanDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Adam LeventhalDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID 0000-0002-1217-525X
Richard J O'ConnorDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Maciej L GoniewiczDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.ORCID 0000-0001-6748-3068
Roswell Park Comprehensive Cancer Center · USUniversity of Southern California · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI CANDACE S JOHNSON · 1985 to 2026
$116.6M
USC Tobacco Center of Regulatory ScienceU54CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jennifer Beth Unger · 2018 to 2026
$39.0M
WNY Center for Research on Flavored Tobacco Products (CRoFT)U54CA228110 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI OSSIP, DEBORAH J · 2018 to 2022
$19.8M
Tobacco Use Treatment Research for Vulnerable PopulationsK24DA048160 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Adam Matthew Leventhal · 2019 to 2026
$1.4M
NCI NIH HHS P30 CA016056NCI NIH HHS U54 CA180905NCI NIH HHS U54 CA228110NIDA NIH HHS K24 DA048160
6 · The paper itself

Abstract

introductionIn December 2022, California (CA) enforced a voter-approved regulation restricting the retail sale of flavoured tobacco products, including menthol cigarettes. Shortly after, new products emerged on the market containing similar blue and green package colours yet with 'non-menthol' descriptors. Using chemical analyses, we measured the content of menthol and 15 other cooling chemicals in Californian cigarettes with 'non-menthol' descriptors and compared concentrations to similar 'menthol'-labelled counterparts available in New York State (NY).

methodsA convenience sample of 10 brands and types of cigarettes in CA were purchased based on package colours suggesting a cooling effect and/or 'non-menthol' descriptors. The exact brand and type of cigarettes (with menthol descriptors) were purchased in NY. Cigarettes from CA were compared with equivalent cigarettes from NY on package design and colours, cigarette physical characteristics and the presence of cooling additives.

resultsMenthol was not detected in any CA cigarette, except for Maverick-green box type, while its presence was confirmed in most NY counterpart products. A synthetic cooling chemical WS-3 was not detected in any NY cigarettes but was detected in four CA brands and types with implied cooling effect, ranging from 1.24±0.04 to 1.97±0.05 mg/cigarette.

conclusionWhile manufacturers have removed menthol descriptors from CA packaging and the menthol ingredient from cigarettes, synthetic cooling chemicals detected in several CA brands suggest that cooling sensory effects may still be sustained. Policymakers must consider both the chemical ingredients themselves and sensory effects in future regulatory approaches.

Indexed as

Flavoring AgentsMentholTobacco IndustryTobacco ProductsCaliforniaCommerceHumansNew YorkProduct LabelingProduct PackagingFlavoring AgentsMentholPackaging and LabellingPublic policyTobacco industry

Identifiers

PMID37500508
PMCPMC12015054
OpenAlexW4385302197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.