Evidence map›Paper›PMID 37500005›Full record

ArticleEuropean journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery2024

Intra-arterial Fractional Flow Reserve Measurements Provide an Objective Assessment of the Functional Significance of Peripheral Arterial Stenoses.

Mostafa A Albayati, Ashish Patel, Bhavik Modi, Prakash Saha, Lawen Karim, Divaka Perera, Alberto Smith, Bijan Modarai, Guy's and St Thomas' Limb Salvage Research Collaborative

Open access · hybridAbstract read
In one paragraph

Article in European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. [Application advances of fractional flow reserve in endovascular treatment of lower-extremity arterial disease].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  8. Review
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mostafa A AlbayatiAcademic Department of Vascular Surgery, Guy's & St Thomas' NHS Foundation Trust and King's College London, United Kingdom.
Ashish PatelAcademic Department of Vascular Surgery, Guy's & St Thomas' NHS Foundation Trust and King's College London, United Kingdom.
Bhavik ModiDepartment of Cardiology, School of Cardiovascular and Metabolic Medicine and Sciences, King's BHF Centre of Excellence, Guy's & St Thomas' NHS Foundation Trust and King's College London, United Kingdom.
Prakash SahaAcademic Department of Vascular Surgery, Guy's & St Thomas' NHS Foundation Trust and King's College London, United Kingdom.
Lawen KarimAcademic Department of Vascular Surgery, Guy's & St Thomas' NHS Foundation Trust and King's College London, United Kingdom.
Divaka PereraDepartment of Cardiology, School of Cardiovascular and Metabolic Medicine and Sciences, King's BHF Centre of Excellence, Guy's & St Thomas' NHS Foundation Trust and King's College London, United Kingdom.
Alberto SmithAcademic Department of Vascular Surgery, Guy's & St Thomas' NHS Foundation Trust and King's College London, United Kingdom.
Bijan ModaraiAcademic Department of Vascular Surgery, Guy's & St Thomas' NHS Foundation Trust and King's College London, United Kingdom. Electronic address: bijan.modarai@kcl.ac.uk.
Guy's and St Thomas' Limb Salvage Research CollaborativeGuy's and St. Thomas' NHS Foundation Trust and King's College London, United Kingdom.
King's College London · GB

Funding

British Heart Foundation FS/16/50/32337British Heart Foundation FS/17/24/32596
6 · The paper itself

Abstract

objectivePeripheral arterial stenoses (PAS) are commonly investigated with duplex ultrasound (DUS) and angiography, but these are not functional tests. Fractional flow reserve (FFR), a pressure based index, functionally assesses the ischaemic potential of coronary stenoses, but its utility in PAS is unknown. FFR in the peripheral vasculature in patients with limb ischaemia was investigated.

methodsPatients scheduled for angioplasty and or stenting of isolated iliac and superficial femoral artery stenoses were recruited. Resting trans-lesional pressure gradient (P

resultsForty-one patients (32, 78%, male, mean age 65 ± 11 years) with 61 stenoses (iliac 32; femoral 29) were studied. For lesions < 80% stenosis, resting P

conclusionThis pilot study demonstrates that FFR can objectively measure the functional significance of PAS that compares favourably with visual and DUS based assessments. Its role as a quality control adjunct that confirms optimal vessel patency after angioplasty and or stenting also merits further investigation.

Indexed as

Coronary StenosisFractional Flow Reserve, MyocardialAgedConstriction, PathologicCoronary AngiographyFemaleHumansMaleMiddle AgedPilot ProjectsPredictive Value of TestsSeverity of Illness IndexAngioplastyFractional flow reserveHaemodynamicPeripheral arterial diseaseStenting

Identifiers

PMID37500005
PMCPMC10917690
OpenAlexW4385319742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.