ReviewProgress in retinal and eye research2023
Optical coherence tomography angiography in diabetic retinopathy.
Review in Progress in retinal and eye research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
104 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.
- Retinal microvascular alterations in sickle cell disease: a systematic review and meta-analysis of OCTA findings based on genotype and stages of retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Pooled it
- Imaging biomarkers in diabetic macular oedema: Predicting vision beyond retinal thickness.Eye (London, England) · 2026Article
- Systemic Diseases and the Eye: A Translational Perspective on Diabetes.Chronic diseases and translational medicine · 2026Review
- Impact of Optical Coherence Tomography Angiography Scan Protocols on Quantitative Microvascular Biomarkers in Diabetic Retinopathy.Translational vision science & technology · 2026Article
- Multimodal Retinal Structural and Functional Tests Identify Local and Layer-Related Alterations in Early Type 2 Diabetes.Investigative ophthalmology & visual science · 2026Article
- Deep Learning Assessment of Intraretinal Microvascular Abnormalities in Diabetic Retinopathy on Swept-Source OCT Angiography.Ophthalmology science · 2026Article
- Outer Retinal Volume on Macular OCT Predicts Two-Year Diabetic Retinopathy Progression.Investigative ophthalmology & visual science · 2026Observational
- Abnormal Glycaemic Fluctuations Associated With Early Microvascular Changes in the Retina and Choroid of Nondiabetic Adults.Diabetes, obesity & metabolism · 2026Article
- AI-driven multimodal retinal imaging for early detection and risk stratification of vascular and neurodegenerative diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Review
- Baseline Deep Capillary Plexus Ischemia Predicts Earlier Diabetic Retinopathy Complications Than Foveal Avascular Enlargement.American journal of ophthalmology · 2026Article
- Axial Length Estimation Using Metadata From Swept-Source Optical Coherence Tomography Angiography.Investigative ophthalmology & visual science · 2026Observational
- Article
- Case series: The role of retinal ischemia in the pathogenesis and clinical manifestation of diabetic retinopathy.Optometry and vision science : official publication of the American Academy of Optometry · 2026Article
- Advances in diagnosing and treating diabetic retinopathy.Nature reviews. Endocrinology · 2026Review
- Explicit Inclusion of Diabetes Mellitus Without Retinopathy Within Diabetic Retinopathy Prediction.Translational vision science & technology · 2026Article
- Capillary-Large Vessel Segmentation on OCTA for Predicting Anti-VEGF Treatment Outcomes in Diabetic Macular Edema.Journal of personalized medicine · 2026Article
- Sorafenib nanoparticles coated with Eudragit RL for ocular drug delivery: a potential treatment for diabetic retinopathy.International journal of pharmaceutics: X · 2026Article
- Enhanced deep learning model for prediction of diabetic mellitus on optical coherence tomography angiography images.Quantitative imaging in medicine and surgery · 2026Article
- Qualitative and Quantitative Assessment of Restored Capillary Perfusion on OCT Angiography in Diabetic Macular Ischemia.Translational vision science & technology · 2026Article
- Prognostic Imaging Biomarkers in Diabetic Macular Edema Treated with Anti-VEGF: A Multicenter AI Perspective.Ophthalmology and therapy · 2026Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
Abstract
There remain many unanswered questions on how to assess and treat the pathology and complications that arise from diabetic retinopathy (DR). Optical coherence tomography angiography (OCTA) is a novel and non-invasive three-dimensional imaging method that can visualize capillaries in all retinal layers. Numerous studies have confirmed that OCTA can identify early evidence of microvascular changes and provide quantitative assessment of the extent of diseases such as DR and its complications. A number of informative OCTA metrics could be used to assess DR in clinical trials, including measurements of the foveal avascular zone (FAZ; area, acircularity, 3D para-FAZ vessel density), vessel density, extrafoveal avascular zones, and neovascularization. Assessing patients with DR using a full-retinal slab OCTA image can limit segmentation errors and confounding factors such as those related to center-involved diabetic macular edema. Given emerging data suggesting the importance of the peripheral retinal vasculature in assessing and predicting DR progression, wide-field OCTA imaging should also be used. Finally, the use of automated methods and algorithms for OCTA image analysis, such as those that can distinguish between areas of true and false signals, reconstruct images, and produce quantitative metrics, such as FAZ area, will greatly improve the efficiency and standardization of results between studies. Most importantly, clinical trial protocols should account for the relatively high frequency of poor-quality data related to sub-optimal imaging conditions in DR and should incorporate time for assessing OCTA image quality and re-imaging patients where necessary.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.