Evidence map›Paper›PMID 37499280›Full record

ArticleAddictive behaviors2023

Pain is associated with exclusive use and co-use of tobacco and cannabis: Findings from Wave 5 (2018-2019) of the Population Assessment of Tobacco and Health Study.

Dana Rubenstein, F Joseph McClernon, Jessica M Powers, Elizabeth R Aston, Francis J Keefe, Maggie M Sweitzer

Open access · greenAbstract read
In one paragraph

Article in Addictive behaviors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dana RubensteinDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27705, United States; Clinical and Translational Science Institute, Duke University School of Medicine, Durham, NC 27705, United States. Electronic address: dana.rubenstein@duke.edu.
F Joseph McClernonDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27705, United States; Clinical and Translational Science Institute, Duke University School of Medicine, Durham, NC 27705, United States.
Jessica M PowersDepartment of Psychology, Syracuse University, Syracuse, NY 13244, United States.
Elizabeth R AstonCenter for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI 02903, United States; Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI 02903, United States.
Francis J KeefeDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27705, United States.
Maggie M SweitzerDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27705, United States.
Duke University · USBrown University · USSyracuse University · US

Funding

NRSA Training CoreTL1TR002555 · NCATS · DUKE UNIVERSITY · PI EDELMAN, DAVID · 2018 to 2022
$3.7M
NCATS NIH HHS TL1 TR002555
6 · The paper itself

Abstract

introductionRates of tobacco and cannabis use are disproportionately high among individuals with pain, and evidence suggests that pain may engender greater likelihood of substance co-use, yielding additive risk. This study examined national associations of pain with past-month tobacco use, cannabis use, and co-use of tobacco and cannabis.

methodsData came from a nationally representative US sample of adults in Wave 5 (2018-2019) of the Population Assessment of Tobacco and Health study (N = 32,014). The sample included civilian, non-institutionalized people who use tobacco and people who do not use tobacco. Past-week pain intensity (0-10) was dichotomized (0-4 no/low pain; 5-10 moderate/severe pain). Multinomial models adjusted for demographics examined substance use category membership (no tobacco or cannabis use, exclusive cannabis use, exclusive tobacco use, co-use) as a function of pain status.

resultsModerate/severe pain was associated with increased relative risk of exclusive tobacco use (RRR [CI] 2.26 [2.05, 2.49], p <.001), exclusive cannabis use (1.49 [1.22, 1.82], p <.001), and co-use of tobacco and cannabis (2.79 [2.51, 3.10], p <.001), in comparison to no tobacco or cannabis use. Additionally, moderate/severe pain was associated with increased risk of co-use compared to exclusive tobacco use (1.23 [1.11, 1.37], p <.001) and exclusive cannabis use (1.88 [1.54, 2.29], p <.001). DISCUSSION: Findings suggest that not only is pain independently associated with greater risk of exclusively using tobacco or cannabis, but pain is also associated with heightened risk of co-using both products. Future work should examine the dynamic and potentially bidirectional relationships between pain and use of cannabis and tobacco.

Indexed as

CannabisSubstance-Related DisordersTobacco ProductsAdultHumansPainTobacco UseCannabisCo-usePainTobacco

Identifiers

PMID37499280
PMCPMC10460575
OpenAlexW4385222943

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.