Evidence map›Paper›PMID 37498916›Full record

ArticlePloS one2023

Protocol for a pilot randomized controlled trial of a telehealth-delivered counseling intervention to reduce suicidality and improve HIV care engagement in Tanzania.

Brandon A Knettel, Elizabeth T Knippler, Ismail Amiri, Louise Joel, Kim Madundo, Elizabeth F Msoka, Judith Boshe, Clotilda S Tarimo, Victor Katiti, Jackline Rwakilomba and 7 more

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Brandon A KnettelDuke University School of Nursing, Durham, NC, United States of America.ORCID 0000-0003-2986-1579
Elizabeth T KnipplerDuke University School of Nursing, Durham, NC, United States of America.
Ismail AmiriDuke Global Health Institute, Durham, NC, United States of America.
Louise JoelKilimanjaro Christian Medical Centre, Moshi, Tanzania.
Kim MadundoKilimanjaro Christian Medical Centre, Moshi, Tanzania.ORCID 0000-0003-0927-1678
Elizabeth F MsokaKilimanjaro Christian Medical Centre, Moshi, Tanzania.
Judith BosheKilimanjaro Christian Medical Centre, Moshi, Tanzania.
Clotilda S TarimoKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Victor KatitiKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Jackline RwakilombaKilimanjaro Christian Medical Centre, Moshi, Tanzania.
Elizabeth L TurnerDuke Global Health Institute, Durham, NC, United States of America.
Linda MinjaKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Catherine A StatonDuke Global Health Institute, Durham, NC, United States of America.
Joao Ricardo N VissociDuke Global Health Institute, Durham, NC, United States of America.
Blandina T MmbagaDuke Global Health Institute, Durham, NC, United States of America.ORCID 0000-0002-5550-1916
Michael V RelfDuke University School of Nursing, Durham, NC, United States of America.
David B GoldstonDepartment of Psychiatry & Behavioral Sciences, Duke University, Durham, NC, United States of America.
Kilimanjaro Christian Medical Centre · TZDuke University · USDuke Institute for Health Innovation · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
NIAID NIH HHS P30 AI064518
6 · The paper itself

Abstract

objectiveSuicidal ideation is strikingly common among people living with HIV (PLWH) worldwide, leading to higher burden of disease, poor HIV care engagement, and loss of life. In low- and middle-income countries such as Tanzania, mental health resources are scarce, requiring innovative strategies for treatment. We describe the protocol for a clinical trial of a three-session telehealth counseling intervention to reduce suicidality and improve HIV care engagement in Tanzania.

methodsIn a pilot randomized controlled trial, we will assess the feasibility, acceptability, and potential efficacy of a new telehealth intervention, termed "IDEAS for Hope". A total of 60 PLWH will be enrolled from two HIV clinics in the Kilimanjaro region and connected to telehealth counsellors based at a large regional hospital. Participants will be ≥18 years old and speak either Kiswahili or English. Patient screening will occur during routine HIV clinical care to identify PLWH experiencing suicidal ideation. Baseline surveys will be administered upon enrollment and participants will be randomized 1:1 to receive either IDEAS for Hope or the comparison condition, a brief safety planning session. All participants will receive an additional referral for psychiatric treatment. Follow-up assessment will occur at three months. IDEAS for Hope is informed by a Motivational Interviewing-enhanced safety planning intervention (MI-SafeCope) and our formative work in Tanzania. The model consists of Four Pillars: living healthy with HIV, managing HIV stigma, seeking social support, and meeting basic needs. Together, these mechanisms serve as a foundation for developing a sense of safety and hope for the future. Outcome measures will include intervention feasibility, acceptability, participant suicidality, and HIV care engagement. SIGNIFICANCE: Innovative, telehealth-based counseling represents a promising treatment for suicidality among PLWH in low-resource settings. Results from this pilot trial will inform intervention refinement and parameter estimates for a future clinical trial powered to evaluate effectiveness.

Indexed as

HIV InfectionsSuicideTelemedicineAdolescentCounselingHumansPilot ProjectsRandomized Controlled Trials as TopicSuicidal IdeationTanzania

Identifiers

PMID37498916
PMCPMC10374000
OpenAlexW4385299425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.