Evidence map›Paper›PMID 37498410›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2023

Measuring symptoms and toxicities: a 35-year experience.

Charles L Loprinzi, Paul Novotny, Kathryn J Ruddy, Aminah Jatoi, Jennifer Le-Rademacher, Shawna L Ehlers, Elizabeth Cathcart-Rake, Minji Lee

Abstract readReview
PubMed Publisher
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Charles L LoprinziMayo Clinic Rochester (Medical Oncology), Rochester, MN, USA. cloprinzi@mayo.edu.ORCID http://orcid.org/0000-0001-8044-5752
Paul NovotnyMayo Clinic Rochester (Division of Clinical Trials and Biostatistics), Rochester, MN, USA.
Kathryn J RuddyMayo Clinic Rochester (Medical Oncology), Rochester, MN, USA.
Aminah JatoiMayo Clinic Rochester (Medical Oncology), Rochester, MN, USA.
Jennifer Le-RademacherMayo Clinic Rochester (Division of Clinical Trials and Biostatistics), Rochester, MN, USA.
Shawna L EhlersMayo Clinic Rochester (Psychiatry & Psychology), Rochester, MN, USA.
Elizabeth Cathcart-RakeMayo Clinic Rochester (Medical Oncology), Rochester, MN, USA.
Minji LeeMayo Clinic Rochester (Division of Clinical Trials and Biostatistics), Rochester, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhen conducting trials aimed at the improvement of cancer-related and/or cancer treatment-related toxicities, it is important to determine the best means of measuring patients' symptoms.

methodsThe authors of this current manuscript have an extensive experience with the conduct of symptom-control clinical trials. This experience is utilized to provide insight into the best means of measuring symptoms caused by cancer and/or cancer therapy.

resultsPatient-reported outcome data are preferable for measuring bothersome symptoms, for determining toxicities caused by treatment approaches, and offer more accurate and detailed information compared with health care practitioners recording their impressions of patient experiences. Well-validated patient friendly measures are recommended when they are available. When such are not readily available, face-valid, single-item numerical rating scales are effective instruments to document both treatment trial outcomes and cancer treatment side effects/toxicities.

conclusionThe use of numerical rating scales are effective means of measuring symptoms caused by cancer, by cancer treatments, and/or alleviated by symptom control treatment approaches.

Indexed as

NeoplasmsHumansTreatment OutcomeClinical trialsMeasuringPatient-reported outcomes

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.