Evidence map›Paper›PMID 37498376›Full record

ArticleInflammopharmacology2023

Essential oil from leaves of Myrciaria floribunda (H. West ex Willd.) O. Berg has antinociceptive and anti-inflammatory potential.

Priscilla Glazielly Dos Santos de Moraes, Izabelly Bianca da Silva Santos, Valquíria Bruna Guimarães Silva, Júlio César Ribeiro Dede Oliveira FariasAguiar, Daniela Maria do Amaral Ferraz Navarro, Alisson Macário de Oliveira, Maria Tereza Dos Santos Correia, Wêndeo Kennedy Costa, Márcia Vanusa da Silva

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Priscilla Glazielly Dos Santos de MoraesDepartamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil.
Izabelly Bianca da Silva SantosDepartamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil.
Valquíria Bruna Guimarães SilvaDepartamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil.
Júlio César Ribeiro Dede Oliveira FariasAguiarDepartamento de Química Fundamental, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil.
Daniela Maria do Amaral Ferraz NavarroDepartamento de Química Fundamental, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil.
Alisson Macário de OliveiraDepartamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil.
Maria Tereza Dos Santos CorreiaDepartamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil.
Wêndeo Kennedy CostaDepartamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil. wendeocosta@gmail.com.ORCID http://orcid.org/0000-0001-7925-6794
Márcia Vanusa da SilvaDepartamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil.
Universidade Federal de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myrciaria floribunda is a plant that is distributed across different Brazilian biomes such as the Amazon, Caatinga, Cerrado, and Atlantic Forest, and it possesses antioxidant, antimicrobial, and anticancer properties. The antinociceptive and anti-inflammatory properties of the essential oil from M. floribunda leaves (MfEO) were examined in this study using mouse models. Gas chromatography-mass spectrometry was employed to describe the oil, and the results revealed that δ-cadinene, bicyclogermacrene, α-cadinol, and epi-α-muurolol predominated in the chemical profile. The oil stimulated a decrease in nociception in the chemical and thermal models used to evaluate acute antinociceptive activity. Findings from the use of pain pathway blockers to study the presumed underlying mechanism indicated opioid pathway activity. The anti-edematogenic effect, decreased cell migration, and generation of pro-inflammatory cytokines provided evidence of the anti-inflammatory potential of the essential oil from M. floribunda. According to this research, the essential oil from M. floribunda can effectively alleviate acute pain and inflammation.

Indexed as

Anti-Infective AgentsOils, VolatileAnalgesicsAnimalsAnti-Inflammatory AgentsAntioxidantsMicePlant ExtractsPlant LeavesAnalgesicsAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsOils, VolatilePlant ExtractsCaatingaCytokinesInflammationMyrtaceaePain

Identifiers

PMID37498376
OpenAlexW4385294912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.