Evidence map›Paper›PMID 37498286›Full record

ArticleJournal of feline medicine and surgery2023

Specificity of a pancreatic lipase point-of-care test and agreement with pancreatic lipase immunoreactivity in cats without clinical evidence of pancreatitis.

Panagiotis G Xenoulis, Katerina T Moraiti, Victoria M Spanou, Manolis K Chatzis, Kassiopi Cg Kokkinaki, Manolis N Saridomichelakis, Jörg M Steiner

Open access · diamondAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Panagiotis G XenoulisClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece.ORCID 0000-0002-9508-0271
Katerina T MoraitiClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece.ORCID 0000-0002-1070-6758
Victoria M SpanouClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece.ORCID 0000-0001-8533-7160
Manolis K ChatzisClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece.
Kassiopi Cg KokkinakiClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece.
Manolis N SaridomichelakisClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece.
Jörg M SteinerGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.ORCID 0000-0003-3336-2086
University of Thessaly · GRTexas A&M University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to determine the specificity of a rapid point-of-care test for the estimation of feline pancreatic lipase (SNAP fPL) in healthy and sick cats without clinical evidence of pancreatitis. A second objective was to evaluate the agreement between SNAP fPL and serum pancreatic lipase immunoreactivity (fPLI), as measured by Spec fPL.

methodsA total of 150 cats were prospectively enrolled into this study. Of them, 82 cats were healthy while 68 cats had various diseases but no clinical signs (eg, anorexia, depression, vomiting) raising a suspicion of pancreatitis.

resultsSNAP fPL was normal in 133/150 cats (specificity 89%) without obvious clinical pancreatitis. SNAP fPL was normal in 74/82 healthy cats (specificity 90%) and in 59/68 cats that were sick but without typical signs of pancreatitis (specificity 87%). The agreement between SNAP fPL and Spec fPL was substantial (k = 0.64) in healthy cats and almost perfect (k = 0.93) in sick cats. The overall agreement between SNAP fPL and Spec fPL was almost perfect (k = 0.81). CONCLUSIONS AND RELEVANCE: The specificity of SNAP fPL in this group of cats was high. There was a substantial and almost perfect agreement between the SNAP fPL and Spec fPL in healthy cats and sick cats without suspected pancreatitis, respectively. In the small percentage of cats with abnormal SNAP fPL and/or Spec fPL results, the possibility of subclinical pancreatitis cannot be excluded.

Indexed as

Cat DiseasesPancreatitisAnimalsCatsLipasePancreasPoint-of-Care TestingVomitingLipaseAgreementdiagnosispancreaspancreatitisSNAP fPLSpec fPLspecificity

Identifiers

PMID37498286
PMCPMC10812057
OpenAlexW4385294559

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.