Evidence map›Paper›PMID 37498085›Full record

ArticlemSphere2023

Relaxed specificity of BcpB transporters mediates interactions between

Zaria K Elery, Tanya Myers-Morales, Erica D Phillips, Erin C Garcia

Abstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zaria K EleryUniversity of Kentucky College of Medicine , Lexington, Kentucky, USA.ORCID 0009-0004-1206-6426
Tanya Myers-MoralesUniversity of Kentucky College of Medicine , Lexington, Kentucky, USA.
Erica D PhillipsUniversity of Kentucky College of Medicine , Lexington, Kentucky, USA.
Erin C GarciaUniversity of Kentucky College of Medicine , Lexington, Kentucky, USA.ORCID 0000-0002-9663-1637

Funding

Structure and function of Burkholderia contact-dependent growth inhibition (CDI) systemsR01AI150767 · NIAID · UNIVERSITY OF KENTUCKY · PI GARCIA, ERIN C · 2020 to 2024
$1.9M
NIAID NIH HHS R01 AI150767
6 · The paper itself

Abstract

Belonging to the two-partner secretion family of proteins, contact-dependent growth inhibition (CDI) systems mediate interbacterial antagonism among closely related Gram-negative bacteria. The toxic portion of a large surface protein, BcpA/CdiA, is delivered to the cytoplasm of neighboring cells where it inhibits growth. Translocation of the antibacterial polypeptide out of the producing cell requires an associated outer membrane transporter, BcpB/CdiB. Some bacteria, including many

Indexed as

Burkholderia cepacia complexHumansMembrane Transport ProteinsMembrane Transport ProteinsBurkholderia dolosaBurkholderia multivoransCDIcontact-dependent growth inhibitioninterbacterial antagonismtwo-partner secretion systemstype Vb secretion

Identifiers

PMID37498085
PMCPMC10449530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.