ReviewBrain : a journal of neurology2023
Speech and language markers of neurodegeneration: a call for global equity.
Review in Brain : a journal of neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06994767 (Speech-derived Digital Biomarkers for Assessing Mild Cognitive Impairment and Alzheimer's Disease Diagnosis Accuracy), which is not on this map. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Speech-derived Digital Biomarkers for Assessing Mild Cognitive Impairment and Alzheimer's Disease Diagnosis Accuracy
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Assessing the prevalence of cognitive impairment among Australians with schizophrenia: A systematic review.The Australian and New Zealand journal of psychiatry · 2026Pooled it
- Speech clocks decode dementia phenotypes, social exposome, and biological aging.Science advances · 2026Article
- Extending standardized speech analysis across languages: An Italian toolkit for transcription and coding of neurological speech.Behavior research methods · 2026Article
- Semantic memory navigation in mild cognitive impairment: Automated markers with neural and biofluid correlates.NeuroImage · 2026Article
- Red ginseng-mediated modulation of the NLRP3 Inflammasome in neuroinflammatory-related cognitive impairments.Journal of ginseng research · 2026Review
- Reported symptoms and patterns of language impairment in bilingual speakers with primary progressive aphasia: a retrospective study.Aphasiology · 2026Article
- SONIVA database: Speech recognition validation in aphasia.Scientific data · 2026Article
- The include network: Advancing cross-linguistic equity in brain health research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Speech-based digital biomarkers for early etiological stratification of Alzheimer's disease and frontotemporal degeneration: a biomarker-confirmed prospective study.The journal of prevention of Alzheimer's disease · 2026Article
- Cross-Lingual Alzheimer's Disease Speech Detection: Polarity Inversion and Few-Shot Calibration Strategies.Bioengineering (Basel, Switzerland) · 2026Article
- Non-verbal dichotic listening: A new cognitive hearing test for dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Benchmarking speech biomarkers of Alzheimer's against cognitive and neural measures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- The landscape of dementia research, diagnosis, treatment, and care in Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Expressive pragmatic language in mood and psychotic disorders: a systematic review and meta-analysis.Schizophrenia (Heidelberg, Germany) · 2026Review
- An interpretable, clinically grounded framework for digital speech biomarker development in neurodegenerative diseases.Frontiers in digital health · 2026Article
- Speech and language outcome measures in clinical trials of Alzheimer's and Parkinson's diseases.Expert review of neurotherapeutics · 2026Review
- Machine Learning-Based Detection of Parkinson's Disease From Arabic Speech: A Cross-Linguistic Validation Study.Journal of central nervous system disease · 2026Article
- Can Language Characteristics Contribute to the Classification of Neurodegenerative Disorders? -An Exploratory Study.Internal medicine (Tokyo, Japan) · 2026Article
- The two faces of elderspeak.NPJ dementia · 2026Review
- Multi-level language deficits in behavioural frontotemporal degeneration and related disorders.Brain communications · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 4 countries.
Funding
Abstract
In the field of neurodegeneration, speech and language assessments are useful for diagnosing aphasic syndromes and for characterizing other disorders. As a complement to classic tests, scalable and low-cost digital tools can capture relevant anomalies automatically, potentially supporting the quest for globally equitable markers of brain health. However, this promise remains unfulfilled due to limited linguistic diversity in scientific works and clinical instruments. Here we argue for cross-linguistic research as a core strategy to counter this problem. First, we survey the contributions of linguistic assessments in the study of primary progressive aphasia and the three most prevalent neurodegenerative disorders worldwide-Alzheimer's disease, Parkinson's disease, and behavioural variant frontotemporal dementia. Second, we address two forms of linguistic unfairness in the literature: the neglect of most of the world's 7000 languages and the preponderance of English-speaking cohorts. Third, we review studies showing that linguistic dysfunctions in a given disorder may vary depending on the patient's language and that English speakers offer a suboptimal benchmark for other language groups. Finally, we highlight different approaches, tools and initiatives for cross-linguistic research, identifying core challenges for their deployment. Overall, we seek to inspire timely actions to counter a looming source of inequity in behavioural neurology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.