Evidence map›Paper›PMID 37497507›Full record

ArticleBiomedical optics express2023

Visualization of surgical maneuvers using intraoperative real-time volumetric optical coherence tomography.

Jianwei D Li, Christian Viehland, Al-Hafeez Dhalla, Robert Trout, William Raynor, Anthony N Kuo, Cynthia A Toth, Lejla M Vajzovic, Joseph A Izatt

Registry-linked trialAbstract read
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07024719 (First Use of Duke 4D Microscope Integrated OCT), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07024719 narecruitingnot on this mapstarted 2025, after this paper: background citation

First Use of Duke 4D Microscope Integrated OCT (MIOCT) Integrated Into Zeiss Artevo 800 Ophthalmic Surgical Microscope in the Operating Room

TypeinterventionalSponsorDuke UniversityRan2025 to 2026Enrolled5ConditionsCorneal Diseases, Retinal Diseases, Ocular DiseasesArms4D MIOCT integrated into a Zeiss Artevo 800
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Real-time Deformation-aware Control for Autonomous Robotic Subretinal Injection under iOCT Guidance.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation · 2025
    Article
  4. Article
  5. New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jianwei D LiDepartment of Biomedical Engineering, 101 Science Drive, Durham, NC 27708, USA.
Christian ViehlandDepartment of Biomedical Engineering, 101 Science Drive, Durham, NC 27708, USA.
Al-Hafeez DhallaDepartment of Biomedical Engineering, 101 Science Drive, Durham, NC 27708, USA.
Robert TroutDepartment of Biomedical Engineering, 101 Science Drive, Durham, NC 27708, USA.ORCID https://orcid.org/0000-0002-6798-6607
William RaynorDepartment of Ophthalmology, Duke University Medical Center, 2351 Erwin Road, Durham, NC 27710, USA.
Anthony N KuoDepartment of Biomedical Engineering, 101 Science Drive, Durham, NC 27708, USA.
Cynthia A TothDepartment of Biomedical Engineering, 101 Science Drive, Durham, NC 27708, USA.
Lejla M VajzovicDepartment of Ophthalmology, Duke University Medical Center, 2351 Erwin Road, Durham, NC 27710, USA.
Joseph A IzattDepartment of Biomedical Engineering, 101 Science Drive, Durham, NC 27708, USA.

Funding

Intraoperative OCT Guidance of Intraocular SurgeryU01EY028079 · NEI · DUKE UNIVERSITY · PI KUO, ANTHONY NANLIN, TOTH, CYNTHIA ANN · 2018 to 2022
$3.8M
NEI NIH HHS U01 EY028079
6 · The paper itself

Abstract

Ophthalmic microsurgery is traditionally performed using stereomicroscopes and requires visualization and manipulation of sub-millimeter tissue structures with limited contrast. Optical coherence tomography (OCT) is a non-invasive imaging modality that can provide high-resolution, depth-resolved cross sections, and has become a valuable tool in clinical practice in ophthalmology. While there has been substantial progress in both research and commercialization efforts to bring OCT imaging into live surgery, its use is still somewhat limited due to factors such as low imaging speed, limited scan configurations, and suboptimal data visualization. In this paper we describe, to the best of our knowledge, the translation of the fastest swept-source intraoperative OCT system with real-time volumetric imaging with stereoscopic data visualization provided via a heads-up display into the operating room. Results from a sampling of human anterior segment and retinal surgeries chosen from 93 human surgeries using the system are shown and the benefits that this mode of intrasurgical OCT imaging provides are discussed.

Identifiers

PMID37497507
PMCPMC10368043

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.