Evidence map›Paper›PMID 37497426›Full record

ArticleTH open : companion journal to thrombosis and haemostasis2023

Effect of PCC on Thrombin Generation among Patients on Factor Xa Inhibitors with Major Bleeding or Needing Urgent Surgery (GAUGE): Design and Rationale.

Joseph R Shaw, Ubabuko Unachukwu, Joseph Cyr, Deborah M Siegal, Lana A Castellucci, Patrick Van Dreden, Dar Dowlatshahi, Hakan Buyukdere, Timothy Ramsay, Marc Carrier

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in TH open : companion journal to thrombosis and haemostasis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06957366 (Perioperative Anticoagulant Use for Surgery Evaluation -2), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06957366 narecruitingnot on this mapstarted 2025, after this paper: background citation

Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure: A Randomized Control Trial

TypeinterventionalSponsorMcMaster UniversityRan2025 to 2027Enrolled920ConditionsAtrial Fibrillation (AF), VTEArmsPAUSE Perioperative DOAC Management, ASRA Perioperative DOAC Management
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Joseph R ShawDepartment of Medicine, Division of Hematology, University of Ottawa, Ottawa, Canada.ORCID 0000-0002-2405-7912
Ubabuko UnachukwuDepartment of Medicine, Division of Hematology, University of Ottawa, Ottawa, Canada.
Joseph CyrDepartment of Medicine, Division of Hematology, University of Ottawa, Ottawa, Canada.
Deborah M SiegalDepartment of Medicine, Division of Hematology, University of Ottawa, Ottawa, Canada.
Lana A CastellucciDepartment of Medicine, Division of Hematology, University of Ottawa, Ottawa, Canada.
Patrick Van DredenDiagnostica Stago, Gennevilliers, France.
Dar DowlatshahiDepartment of Medicine, Division of Hematology, University of Ottawa, Ottawa, Canada.
Hakan BuyukdereDepartment of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Canada.
Timothy RamsayOttawa Hospital Research Institute, Ottawa, Canada.
Marc CarrierDepartment of Medicine, Division of Hematology, University of Ottawa, Ottawa, Canada.
University of Ottawa · CAOttawa Hospital · CAStago (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anticoagulation reversaldabigatranfactor Xa inhibitorshemostasis

Identifiers

PMID37497426
PMCPMC10368490
OpenAlexW4385259228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.