Evidence map›Paper›PMID 37497090›Full record

ArticleRSC advances2023

Engineering of a GSH activatable photosensitizer for enhanced photodynamic therapy through disrupting redox homeostasis.

Datian Fu, Yan Wang, Kaiwen Lin, Liangjiu Huang, Jin Xu, Haimei Wu

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Activatable Photosensitizers: From Fundamental Principles to Advanced Designs.Angewandte Chemie (International ed. in English) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Datian FuDepartment of Pharmacy, Hainan Women and Children's Medical Center Haikou Hainan 570100 China.
Yan WangDepartment of Pharmacy, Hainan Women and Children's Medical Center Haikou Hainan 570100 China.
Kaiwen LinDepartment of Pharmacy, Hainan Women and Children's Medical Center Haikou Hainan 570100 China.
Liangjiu HuangDepartment of Clinical Pharmacy, Hainan Cancer Hospital Haikou Hainan 570100 China wu634202863@126.com.
Jin XuPharmaceutical and Bioengineering School, Hunan Chemical Vocational Technology College Zhuzhou 412006 China.
Haimei WuDepartment of Clinical Pharmacy, Hainan Cancer Hospital Haikou Hainan 570100 China wu634202863@126.com.ORCID https://orcid.org/0000-0001-9457-5339
Hainan Medical College Hospital · CNHunan Vocational Institute of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although disrupted redox homeostasis has emerged as a promising approach for tumor therapy, most existing photosensitizers are not able to simultaneously improve the reactive oxygen species level and reduce the glutathione (GSH) level. Therefore, designing photosensitizers that can achieve these two aspects of this goal is still urgent and challenging. In this work, an organic activatable near-infrared (NIR) photosensitizer, CyI-S-diCF

Identifiers

PMID37497090
PMCPMC10366568
OpenAlexW4385243463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.