Evidence map›Paper›PMID 37497077›Full record

ArticleIEEE sensors journal2022

Capacitive Sensing for 2-D Electrostatic MEMS Scanner in a Clinical Endomicroscope.

Miki Lee, Haijun Li, Mayur B Birla, Gaoming Li, Thomas D Wang, Kenn R Oldham

Open access · greenAbstract read
In one paragraph

Article in IEEE sensors journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Miki LeeDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Haijun LiDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Mayur B BirlaDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Gaoming LiDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Thomas D WangDepartments of Internal Medicine, Biomedical Engineering, and Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Kenn R OldhamDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
University of Michigan · US

Funding

Validation & Pathology CoreU54CA163059 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RUBENSTEIN, JOEL H, WANG, THOMAS D · 2011 to 2022
$12.1M
Microsystems imaging system for epithelial-derived cancer heterogeneityU01EB028235 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OLDHAM, KENN R, WANG, THOMAS D · 2019 to 2023
$2.9M
Early detection of colorectal cancer in the traditional and serrated pathwaysR01CA249851 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, THOMAS D · 2020 to 2024
$1.7M
Multi-Photon endomicroscope for real-time in vivo vertical sectioningR01EB020644 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OLDHAM, KENN R · 2015 to 2018
$1.3M
NCI NIH HHS R01 CA249851NCI NIH HHS U54 CA163059NIBIB NIH HHS R01 EB020644NIBIB NIH HHS U01 EB028235
6 · The paper itself

Abstract

A flexible fiber-coupled confocal laser endomicroscope has been developed using an electrostatic micro-electromechanical system (MEMS) scanner located in at distal optics to collect in vivo images in human subjects. Long transmission lines are required that deliver drive and sense signals with limited bandwidth. Phase shifts have been observed between orthogonal X and Y scanner axes from environmental perturbations, which impede image reconstruction. Image processing algorithms used for correction depend on image content and quality, while scanner calibration in the clinic can be limited by potential patient exposure to lasers. We demonstrate a capacitive sensing method to track the motion of the electrostatically driven two-dimensional MEMS scanner and to extract phase information needed for image reconstruction. This circuit uses an amplitude modulation envelope detection method on shared drive and sensing electrodes of the scanner. Circuit parameters were optimized for performance given high scan frequencies, transmission line effects, and substantial parasitic coupling of drive signal to circuit output. Extraction of phase information further leverages nonlinear dynamics of the MEMS scanner. The sensing circuit was verified by comparing with data from a position sensing detector measurement. The phase estimation showed an accuracy of 2.18° and 0.79° in X and Y axes for motion sensing, respectively. The results indicate that the sensing circuit can be implemented with feedback control for pre-calibration of the scanner in clinical MEMS-based imaging systems.

Indexed as

Capacitive sensingEndomicroscopyImaging systemsMicroelectromechanical Systems (MEMS)MirrorPhase correctionScanner

Identifiers

PMID37497077
PMCPMC10367433
OpenAlexW4311458456

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.