Evidence map›Paper›PMID 37496976›Full record

Article3 Biotech2023

An impedimetric immunosensor based on chitosan-Au nanoparticles-reduced graphene oxide nanosheet composite modified PG electrode for detection of brain natriuretic peptide.

Twinkle Dahiya, Minakshi Sharma, Ravina Rathee, C S Pundir, J S Rana

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Twinkle DahiyaDepartment of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Haryana 131039 India.
Minakshi SharmaDepartment of Zoology, Maharishi Dayanand University, Rohtak, Haryana 124001 India.
Ravina RatheeDepartment of Medical Biotechnology, Maharishi Dayanand University, Rohtak, Haryana 124001 India.
C S PundirDepartment of Biochemistry, Maharishi Dayanand University, Rohtak, Haryana 124001 India.
J S RanaDepartment of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Haryana 131039 India.ORCID 0000-0002-0093-0537
Maharshi Dayanand University · INDeenbandhu Chhotu Ram University of Science and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An ultrasensitive impedimetric immunosensor was developed to detect brain natriuretic peptide (BNP) for early diagnosis of heart failure. To construct this immunosensor, anti-BNP antibodies were immobilized covalently onto nanocomposite of chitosan-Au nanoparticles and reduced graphene oxide nanosheets (CHIT-Au@rGONs) electrodeposited onto pencil graphite electrode. This approach impedes charge transfer resistance (Rct) value proportionally to the BNP captured by antigen-antibody interactions. The observed Rct values by this immunosensor, were correlated with linear concentrations of BNP in the range, 1 × 10 Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-023-03704-x.

Indexed as

Brain natriuretic peptide (BNP)Charge-transfer resistance value (Rct value)Chitosan–gold–graphene oxide nanosheet-compositeElectrochemical impedance spectroscopy (EIS)Human serumImmunosensor

Identifiers

PMID37496976
PMCPMC10366047
OpenAlexW4385225637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.