Evidence map›Paper›PMID 37496955›Full record

ArticleOrganic process research & development2023

Toward Kilogram-Scale Peroxygenase-Catalyzed Oxyfunctionalization of Cyclohexane.

Thomas Hilberath, Remco van Oosten, Juliet Victoria, Hugo Brasselet, Miguel Alcalde, John M Woodley, Frank Hollmann

Abstract read
In one paragraph

Article in Organic process research & development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Empowering Precision C-H Functionalization: Advances in Peroxygenase Engineering.Angewandte Chemie (International ed. in English) · 2026
    Review
  3. Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026
    Review
  4. Article
  5. Article
  6. An Update: Enzymatic Synthesis for Industrial Applications.Angewandte Chemie (International ed. in English) · 2025
    Review
  7. Article
  8. Selective Oxidation of Vitamin DChemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas HilberathDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629HZ Delft, The Netherlands.ORCID https://orcid.org/0000-0002-9778-2509
Remco van OostenDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629HZ Delft, The Netherlands.ORCID https://orcid.org/0000-0002-3850-6125
Juliet VictoriaDepartment of Chemical and Biochemical Engineering, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.ORCID https://orcid.org/0000-0002-8961-0336
Hugo BrasseletAtlant. Innov., Koornmarkt 52, 2611 EH Delft, The Netherlands.
Miguel AlcaldeDepartment of Biocatalysis, Institute of Catalysis, CSIC, 28049 Madrid, Spain.ORCID https://orcid.org/0000-0001-6780-7616
John M WoodleyDepartment of Chemical and Biochemical Engineering, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.ORCID https://orcid.org/0000-0002-7976-2483
Frank HollmannDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629HZ Delft, The Netherlands.ORCID https://orcid.org/0000-0003-4821-756X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mol-scale oxyfunctionalization of cyclohexane to cyclohexanol/cyclohexanone (KA-oil) using an unspecific peroxygenase is reported. Using

Identifiers

PMID37496955
PMCPMC10367066

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.