ArticleInternational journal of clinical pediatric dentistry
Combination Therapy of Antibiotics and Platelet-rich Fibrin for Apical Closure: Case Series.
Article in International journal of clinical pediatric dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Platelet-Rich Plasma and Platelet-Rich Fibrin in Endodontics: A Scoping Review.International journal of molecular sciences · 2025Article
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Authors and funding
6 authors.
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Abstract
The aim of endodontic treatment in immature teeth is to disinfect and regenerate tissues in the apical region for the closure of the root. Stem cells from apical papilla (SCAP) by differentiating into odontogenic and osteogenic tissues create apical closure. Triple antibiotic pastes (TAP) disinfect the root canal without adversely affecting the SCAP. Differentiation of SCAP is promoted by platelet-rich fibrin (PRF). Hence, combining TAP and PRF could have a synergistic effect. Case description: An 11-year-old girl, a 9-year-old boy, and a 13-year-old boy, symptomatic patients with open apex, are treated with TAP, PRF, and mineral trioxide aggregate (MTA) as an apical barrier sequentially. There was the formation of a calcific barrier at the end of 12, 6, and 3 months, respectively. Conclusion: Correct diagnosis and protocol of sequential disinfection, regeneration, and finally filling the canal with an apical barrier could yield better results. How to cite this article: Biradar N, Ragulakollu R, Tej G,
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