ArticleBeilstein journal of nanotechnology2023
Silver-based SERS substrates fabricated using a 3D printed microfluidic device.
Article in Beilstein journal of nanotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Microfluidics-Integrated Spectroscopic Technologies for Food Safety and Quality Assessment: From Complex-Matrix Processing to On-Site Decision-Making.Foods (Basel, Switzerland) · 2026Review
- Study of the Relation Between the Reynolds Number and the Formation of Au and Ag Nanostructures by Flow-Driven Surface Modification in Microfluidic Reactors.Micromachines · 2026Article
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The detection of harmful chemicals in the environment and for food safety is a crucial requirement. While traditional techniques such as GC-MS and HPLC provide high sensitivity, they are expensive, time-consuming, and require skilled labor. Surface-enhanced Raman spectroscopy (SERS) is a powerful analytical tool for detecting ultralow concentrations of chemical compounds and biomolecules. We present a reproducible method for producing Ag nanoparticles that can be used to create highly sensitive SERS substrates. A microfluidic device was employed to confine the precursor reagents within the droplets, resulting in Ag nanoparticles of uniform shape and size. The study investigates the effects of various synthesis conditions on the size distribution, dispersity, and localized surface plasmon resonance wavelength of the Ag nanoparticles. To create the SERS substrate, the as-synthesized Ag nanoparticles were assembled into a monolayer on a liquid/air interface and deposited onto a porous silicon array prepared through a metal-assisted chemical etching approach. By using the developed microfluidic device, enhancement factors of the Raman signal for rhodamine B (at 10
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