Evidence map›Paper›PMID 37496594›Full record

ArticleCase reports in ophthalmology

Ocular Syphilis with Retinal and Disc Neovascularization Treated with Bevacizumab: A Case Report.

Lucia Comastri, Milagros Heredia, Diego Bar, Guillermo Iribarren, Ariel Schlaen

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lucia ComastriHospital Alemán, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.
Milagros HerediaHospital Alemán, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.
Diego BarHospital Alemán, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.
Guillermo IribarrenHospital Alemán, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.
Ariel SchlaenHospital Universitario Austral, Derqui-Pilar, Buenos Aires, Argentina.
Hospital Alemán · ARHospital Universitario Austral · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the findings observed in a young woman with ocular syphilis complicated with retinal and disc neovascularization successfully treated with intravitreal bevacizumab. Fluorescein angiography revealed in both eyes intense hyperfluorescence at the level of the disc, multifocal venous wall staining, multifocal paravenous leakage, multiple peripheral saccular venular dilations, diffuse retinal and macular edema, and retinal and disc neovascularization. There was no evidence of retinal ischemia in both eyes. After antibiotic and corticosteroid treatment, the neovascularization persisted in both eyes. Three consecutive doses of intravitreal bevacizumab were administered, with total regression of the retinal and disc neovascularization. Disc and retinal neovascularization along with nonocclusive retinal vasculitis may be a form of presentation of ocular syphilis. Combination of specific treatment, oral corticosteroids, and intravitreal bevacizumab may be useful for treating this clinical manifestation.

Indexed as

Case reportIntravitreal bevacizumabOcular syphilisRetinal neovascularizationVascular dilation

Identifiers

PMID37496594
PMCPMC10368100
OpenAlexW4385295437

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.