Evidence map›Paper›PMID 37496248›Full record

ArticleCurrent drug research reviews2024

Assessing the Efficacy of Berberine Hydrochloride-loaded Transethosomal Gel System in Treating Dermatophytosis Caused by

Koushlesh Kumar Mishra, Chanchal Deep Kaur, Sunil Singh, Abhishek Tiwari, Varsha Tiwari, Ajay Sharma

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Article in Current drug research reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Koushlesh Kumar MishraDepartment of Pharmacy, Shri Sai College of Pharmacy, Prayagraj, Uttar Pradesh, India.
Chanchal Deep KaurDepartment of Pharmacy, Rungta College of Pharmaceutical Sciences and Research, Near Nandanvan, Raipur, Chhattisgarh, India.
Sunil SinghDepartment of Pharmacy, Shri Sai College of Pharmacy, Prayagraj, Uttar Pradesh, India.
Abhishek TiwariDepartment of Pharmacy, Pharmacy Academy, IFTM University, Lodhipur-Rajput, Moradabad-244102, India.
Varsha TiwariDepartment of Pharmacy, Pharmacy Academy, IFTM University, Lodhipur-Rajput, Moradabad-244102, India.
Ajay SharmaSchool of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, Pushp Vihar, New Delhi 110017, India.
IFTM University · INShri Sathya Sai Medical College and Research Institute · INDelhi Pharmaceutical Science and Research University · INHindu College of Pharmacy · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDermatophytosis is the most common dermatological disorder worldwide. Many drugs are available in the market for the treatment of dermatophytosis, but they have had limited success due to the stratum corneum barrier, antifungal resistance, drug permeation, drug retention in skin layers,

methodsIn this study, we developed an oleic acid-containing berberine-hydrochloride-loaded transethosomal gel for effective treatment of dermatophytosis by

resultsBerberine-hydrochloride-loaded transethosomes seemed to be spherical and found in a range between 200-300 nm. Berberine-hydrochloride-loaded transethosomal gel formulation also exhibited controlled

conclusionTherefore, the incorporation of berberine hydrochloride-loaded transethosomal nanosystems into the gel has the potential to enhance antifungal activity and permeation through transdermal drug delivery.

Indexed as

Antifungal AgentsBerberineGelsTineaTrichophytonAcrylatesAdministration, CutaneousAnimalsArthrodermataceaeDisease Models, AnimalDrug LiberationMaleOleic AcidRatsRats, WistarSkin AbsorptionAcrylatesAntifungal AgentsBerberinecarbopol 934PGelsOleic AcidantifungalBerberine-hydrochloridedermatophytosisnanotechnology.transethosomal gelTrichophyton rubrum

Identifiers

PMID37496248
OpenAlexW4385295645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.