ArticleBMC public health2023
Post COVID-19 condition and health-related quality of life: a longitudinal cohort study in the Belgian adult population.
Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Psychological and Cognitive Sequelae of COVID-19: Systematic Review and Meta-Analysis.Journal of psychiatric and mental health nursing · 2026Pooled it
- Health-related quality of life in COVID-19 patients: a systematic review and meta-analysis of EQ-5D studies.Health and quality of life outcomes · 2025Pooled it
- Symptom Trajectories and Clinical Subtypes in Post-COVID-19 Condition: Systematic Review and Clustering Analysis.JMIR public health and surveillance · 2025Pooled it
- Effects of a symptom-titrated exercise program on fatigue and quality of life in people with post-COVID condition - a randomized controlled trial.Scientific reports · 2024Trial
- Safety and Changes in Health-Related Quality of Life After Epidural Oxygen Injection for Long COVID/Post-COVID Syndrome: A Multicenter Retrospective Study.Journal of clinical medicine · 2026Article
- Psychopathologies in post-COVID outpatients differ from a psychosomatic control sample in a cross-sectional study.Discover mental health · 2026Article
- Association between persistent symptoms and health-related quality of life in the post-COVID-19 condition: a cross-sectional survey in a nationally representative sample of French adults.Health and quality of life outcomes · 2026Article
- Identifying Long Covid phenotypes and their association with personal characteristics, healthcare use, and daily life burden: population-based study in Belgium.Scientific reports · 2026Article
- Estimating Impact of SARS-CoV-2 Infection on Health-Related Quality of Life Among Persons Aged 8 Years and Older, August 2020-July 2022.Journal of health economics and outcomes research · 2026Article
- Comparison of long-term health-related quality of life and symptoms between COVID-19 patients and test-negative controls during the Omicron-predominant period in Japan.Archives of public health = Archives belges de sante publique · 2025Article
- Trajectories of persisting Covid- 19 symptoms up to 24 months after acute infection: findings from the Predi-Covid cohort study.BMC infectious diseases · 2025Observational
- Impact of Long COVID on Health-Related Quality of Life Among COVID-19 Survivors in Saudi Arabia.Healthcare (Basel, Switzerland) · 2025Article
- EQ-5D-3L and EQ-5D-5L population norms for Thailand.BMC public health · 2024Article
- Higher level of physical activity reduces mental and neurological symptoms during and two years after COVID-19 infection in young women.Scientific reports · 2024Article
- Investigating the trajectory of post-COVID impairments: a longitudinal study in Sweden.Frontiers in psychology · 2024Article
- Article
- Advance in the mechanism and clinical research of myalgia in long COVID.American journal of clinical and experimental immunology · 2024Review
- Impact of COVID-19 Infection on Health-Related Quality of Life, Work Productivity and Activity Impairment by Symptom-Based Long COVID Status and Age in the US.Healthcare (Basel, Switzerland) · 2023Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince the onset of the COVID-19 pandemic, most research has focused on the acute phase of COVID-19, yet some people experience symptoms beyond, referred to as post COVID-19 conditions (PCC). However, evidence on PCC and its impacts on health-related quality of life (HRQoL) is still scarce. This study aimed to assess the impact of COVID-19 and PCC on HRQoL.
methodsThis is a longitudinal cohort study of the Belgian adult population with recent SARS-CoV-2 infection. In total, 5,727 people were followed up between the time of their infection and three months later. HRQoL was measured with the EQ-5D-5L questionnaire before and during the infection and three months later. Linear mixed regression models were built to assess the longitudinal association between participants' characteristics and the evolution of their HRQoL.
resultsThis study found a significant decline in HRQoL during the SARS-CoV-2 infection in comparison to the situation before (β=-9.91, 95%CI=-10.13;-9.85), but no clinically important difference three months after the infection compared to the situation before, except among people reporting PCC (β=-11.15, 95%CI=-11.72;-10.51). The main symptoms of PCC with a significant negative impact on the different dimensions of HRQoL were fatigue/exhaustion (21%), headache (11%), memory problems (10%), shortness of breath (9%), and joint (7%) or muscle pain (6%). The dimension of HRQoL most negatively affected by several PCC symptoms was pain/discomfort.
conclusionsWith the growing number of people infected with SARS-CoV-2, PCC and its impact on HRQoL are becoming important public health issues. To allow people with PCC to recover and to limit its detrimental impact on HRQoL, it is essential to manage its various heterogeneous symptoms using a multidisciplinary approach.
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