ArticleNature2023
Evolutionary histories of breast cancer and related clones.
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Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
17.7field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
59 citing papers in PubMed, 74 citations in OpenAlex.
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- Decoding the breast cancer microenvironment by spatial multi-omics: from architecture to clinical translation.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Review
- Motif-Centered Analyses Reveal Universal and Tissue-Specific Mutagenic Mechanisms Operating in the Human Body.bioRxiv : the preprint server for biology · 2026Article
- Tissue-Specific Prevalence and Clonal Architecture ofbioRxiv : the preprint server for biology · 2026Article
- Single-cell spatial atlas of the aging human breast.Nature aging · 2026Article
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- Somatic mutations and clonal evolution in normal tissues and cancer development.Experimental & molecular medicine · 2026Review
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- Field cancerization in urothelial carcinoma: molecular alterations and clinical implications.Journal of Cancer · 2026Review
- Whole-genome landscapes of 1,364 breast cancers.Nature · 2026Article
- Spatially Discontinuous Mutation Topographies in Ductal Carcinoma In Situ Reveal Noncompetitive Growth Dynamics.Cancer research · 2025Article
- Dual Inhibition of PARP and Akt Induces Metabolic Collapse and Apoptosis in Breast Cancer Cells.Cancers · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
40 authors at 7 institutions in 2 countries.
Tomomi Nishimura *Department of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0009-0008-1999-5147
Nobuyuki Kakiuchi *Department of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0003-4893-5414
Kenichi YoshidaDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0003-4612-2778
Takaki SakuraiDepartment of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.
Tatsuki R KataokaDepartment of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.
Eiji KondohDepartment of Gynecology and Obstetrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0002-8379-3143
Yoshitsugu ChigusaDepartment of Gynecology and Obstetrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0001-9629-5912
Masahiko KawaiDepartment of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Morio SawadaAdachi Hospital, Kyoto, Japan.
Takuya InoueAdachi Hospital, Kyoto, Japan.
Yasuhide TakeuchiDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hirona MaedaDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0003-3406-1680
Satoko BabaPathology Project for Molecular Targets, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
Yusuke ShiozawaDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0001-8673-677X
Ryunosuke SaikiDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Masahiro M NakagawaDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0002-6420-2555
Yasuhito NannyaDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yotaro OchiDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tomonori HiranoDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tomoe NakagawaDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0009-0000-0865-9940
Yukiko Inagaki-KawataDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kosuke AokiDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Masahiro HirataDepartment of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.ORCID 0000-0001-9211-0511
Kosaku NankiDepartment of Organoid Medicine, Sakaguchi Laboratory, Keio University School of Medicine, Tokyo, Japan.
Mami MatanoDepartment of Organoid Medicine, Sakaguchi Laboratory, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-9554-5991
Megumu SaitoDepartment of Organoid Medicine, Sakaguchi Laboratory, Keio University School of Medicine, Tokyo, Japan.
Eiji SuzukiDepartment of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Masahiro TakadaDepartment of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0002-5954-1296
Masahiro KawashimaDepartment of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kosuke KawaguchiDepartment of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kenichi ChibaDivision of Genome Analysis Platform Development, National Cancer Center Research Institute, Tokyo, Japan.
Yuichi ShiraishiDivision of Genome Analysis Platform Development, National Cancer Center Research Institute, Tokyo, Japan.
Junko TakitaDepartment of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Satoru MiyanoDepartment of Integrated Analytics, M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.ORCID 0000-0002-1753-6616
Masaki MandaiDepartment of Gynecology and Obstetrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Toshiro SatoDepartment of Organoid Medicine, Sakaguchi Laboratory, Keio University School of Medicine, Tokyo, Japan.
Kengo TakeuchiPathology Project for Molecular Targets, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.ORCID 0000-0002-1599-5800
Hironori HagaDepartment of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.
Masakazu ToiDepartment of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0003-1488-9958
Seishi OgawaDepartment of Pathology and Tumour Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. sogawa-tky@umin.ac.jp.ORCID 0000-0002-7778-5374
Kyoto University · JPKeio University · JPKyoto University Hospital · JPJapanese Foundation For Cancer Research · JPIwate Medical University · JPOtsuka (Japan) · JPTokyo Medical and Dental University · JP
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies have documented frequent evolution of clones carrying common cancer mutations in apparently normal tissues, which are implicated in cancer development
Indexed as
Breast NeoplasmsCell LineageClone CellsEvolution, MolecularMutagenesisMutationAdolescentAdultEpigenesis, GeneticEpithelial CellsEpitheliumFemaleHumansMicrodissectionMutation RatePremenopauseAKT1 protein, humanProto-Oncogene Proteins c-akt
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.