ArticleScientific reports2023
Effect of gold nanoparticles distribution radius on photothermal therapy efficacy.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Numerical optimization of laser radius ratio and power in photothermal therapy of various ellipsoidal tumor shape.Discover nano · 2026Article
- Development of Gold coated calcium peroxide nanoparticles for photothermal ferroptosis against skin cancer and C. albicans.Communications chemistry · 2026Article
- Integrated tissue and serum proteomics on magnet-guided photothermal therapy using Au/Fe/Au trilayer nanodiscs.Scientific reports · 2025Article
- Nanoparticle enhanced coupled bioheat vapor bubble model and simulation for LITT in breast tumors.Lasers in medical science · 2025Article
- Laser irradiation of human skin tissue after gold nanoparticles injection for thermal ablation processes - a combined experimental and numerical approach.Scientific reports · 2025Article
- Towards a Less Invasive Treatment for Head and Neck Cancer: Initial Evaluation of Gold Nanoparticle-Mediated Photothermal Therapy.Pharmaceutics · 2025Article
- Monte Carlo Simulations in Nanomedicine: Advancing Cancer Imaging and Therapy.Nanomaterials (Basel, Switzerland) · 2025Review
- Characterization of the Optical Properties of Photoluminescent Turbid Media Using an Integrating Sphere and Monte Carlo Simulations.Materials (Basel, Switzerland) · 2024Article
- Analysis of Peri-Implantitis Photothermal Therapy Effect According to Laser Irradiation Location and Angle: A Numerical Approach.Biomedicines · 2024Article
- Enhancing tumor's skin photothermal therapy using Gold nanoparticles : a Monte Carlo simulation.Lasers in medical science · 2024Article
- Analysis of Optimal Treatment Starting Time for Photothermal Therapy Through Analysis of Diffusion Behavior of Gold Nanoparticles.International journal of nanomedicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lasers are used in various fields, however, in the medical field, they are mainly used for incision or chemotherapy. Photothermal therapy (PTT) is an anti-cancer treatment technique that uses lasers and the photothermal effect to increase the temperature of tumor tissue and induce its death. In this study, the therapeutic effect of PTT using gold nanoparticles as a photothermal converter was analyzed numerically for the occurrence of squamous cell carcinoma inside a skin section consisting four layers. Numerical modeling was implemented to calculate the temperature distribution inside the biological tissue while varying the distribution radius of gold nanoparticles in the tumor tissue, the number of injections, and the intensity of the irradiating laser. For the given situation, the optimal treatment effect was observed when the distribution radius ratio of the injected gold nanoparticles (GNPs) was 1, the number of injections was 7, and the intensity of the irradiated laser was 52 mW. Three apoptotic variables were used to quantitively evaluate the effect of PTT in each case and thus suggest the optimal treatment effect. However, although the temperature range at which apoptosis occurs is known, the maintenance of that temperature range is still under research and the temporal influence of apoptosis remains to be determined.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.