Evidence map›Paper›PMID 37495589›Full record

ArticleNature communications2023

Self-organization of primitive metabolic cycles due to non-reciprocal interactions.

Vincent Ouazan-Reboul, Jaime Agudo-Canalejo, Ramin Golestanian

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. The 2025 motile active matter roadmap.Journal of physics. Condensed matter : an Institute of Physics journal · 2025
    Review
  5. Emergent polar order in nonpolar mixtures with nonreciprocal interactions.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Self-Organized Patterns in Non-Reciprocal Active Droplet Systems.Angewandte Chemie (International ed. in English) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vincent Ouazan-ReboulMax Planck Institute for Dynamics and Self-Organization, Am Fassberg 17, D-37077, Göttingen, Germany.
Jaime Agudo-CanalejoMax Planck Institute for Dynamics and Self-Organization, Am Fassberg 17, D-37077, Göttingen, Germany.ORCID http://orcid.org/0000-0001-9677-6054
Ramin GolestanianMax Planck Institute for Dynamics and Self-Organization, Am Fassberg 17, D-37077, Göttingen, Germany. ramin.golestanian@ds.mpg.de.ORCID http://orcid.org/0000-0002-3149-4002

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the greatest mysteries concerning the origin of life is how it has emerged so quickly after the formation of the earth. In particular, it is not understood how metabolic cycles, which power the non-equilibrium activity of cells, have come into existence in the first instances. While it is generally expected that non-equilibrium conditions would have been necessary for the formation of primitive metabolic structures, the focus has so far been on externally imposed non-equilibrium conditions, such as temperature or proton gradients. Here, we propose an alternative paradigm in which naturally occurring non-reciprocal interactions between catalysts that can partner together in a cyclic reaction lead to their recruitment into self-organized functional structures. We uncover different classes of self-organized cycles that form through exponentially rapid coarsening processes, depending on the parity of the cycle and the nature of the interaction motifs, which are all generic but have readily tuneable features.

Identifiers

PMID37495589
PMCPMC10372013

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.