Evidence map›Paper›PMID 37495571›Full record

ArticleNPJ Parkinson's disease2023

Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson's disease primate model.

Ibrahim Kaya, Anna Nilsson, Dominika Luptáková, Yachao He, Theodosia Vallianatou, Patrik Bjärterot, Per Svenningsson, Erwan Bezard, Per E Andrén

Open access · goldAbstract read
In one paragraph

Article in NPJ Parkinson's disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  7. ExploringFrontiers in cell and developmental biology · 2026
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  13. Cellular fibronectin exacerbates α-synuclein aggregation via integrin alpha4beta1 mediated PARP1 and SCD elevation.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ibrahim KayaDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Anna NilssonDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Dominika LuptákováDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0002-3691-2584
Yachao HeSection of Neurology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-0241-2901
Theodosia VallianatouDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0002-1477-7756
Patrik BjärterotDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0002-4350-5530
Per SvenningssonSection of Neurology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-6727-3802
Erwan BezardUniversity of Bordeaux, CNRS, IMN, UMR 5293, F-33000, Bordeaux, France.ORCID http://orcid.org/0000-0002-0410-4638
Per E AndrénDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. per.andren@uu.se.ORCID http://orcid.org/0000-0002-4062-7743
Uppsala University · SEKarolinska Institutet · SECentre National de la Recherche Scientifique · FR

Funding

Agence Nationale de la Recherche (French National Research Agency) ANR-07-MNP TRAFINLIDAgence Nationale de la Recherche (French National Research Agency) ANR-08-MNP-018 MCHPRIMAPARKHjärnfonden (Swedish Brain Foundation) FO2021-0318Stiftelsen för Strategisk Forskning (Swedish Foundation for Strategic Research) RIF14-0078Vetenskapsrådet (Swedish Research Council) 2021-03293Vetenskapsrådet (Swedish Research Council) 2022-04198
6 · The paper itself

Abstract

Metabolism of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) to the neurotoxin MPP

Identifiers

PMID37495571
PMCPMC10372136
OpenAlexW4385266492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.