Evidence map›Paper›PMID 37495518›Full record

ArticleThe Journal of veterinary medical science2023

Pyruvate kinase deficiency mutant gene carriage in stray cats and rescued cats from animal hoarding in Hokkaido, Japan.

Hiroshi Ueno, Tomohito Itoh, Toyohiko Nasuno, Wataru Konno, Atsushi Kondo, Ikuo Konishi, Hisao Inukai, Daiki Kokubo, Mitsuhiro Isaka, Md Shafiqul Islam and 1 more

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. From Mutation to Manifestation: Evaluation of aAnimals : an open access journal from MDPI · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Hiroshi UenoDepartment of Companion Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
Tomohito ItohMaebashi Institute of Animal Science, Livestock Improvement Association of Japan, Inc., Gumma, Japan.
Toyohiko NasunoNekoiro Clinic, Hokkaido, Japan.
Wataru KonnoDepartment of Companion Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
Atsushi KondoTakahashi Animal Hospital, Hokkaido, Japan.
Ikuo KonishiPalk Animal Hospital, Hokkaido, Japan.
Hisao InukaiNeko-no-byoin, Hokkaido, Japan.
Daiki KokuboDepartment of Companion Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
Mitsuhiro IsakaDepartment of Companion Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
Md Shafiqul IslamLaboratory of Clinical Pathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Osamu YamatoLaboratory of Clinical Pathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Rakuno Gakuen University · JPKagoshima University · JPInstitute of Livestock and Grassland Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mutant allele frequency of the Pyruvate kinase (PK) gene has been investigated mostly in pure breed cats. We investigated the PK mutant gene in stray and animal hoarding mongrel cats in Hokkaido, Japan. We also investigated the kinship of individuals carrying the mutant gene. Genotyping was conducted using the previously reported real-time PCR method. Fourteen microsatellite markers were used to identify the parents and offspring of cats carrying the PK mutant gene, and some kinship such as parent-offspring and siblings was observed. Some stray and animal hoarding cats carried the PK mutation gene and that consanguinity was confirmed among these cats indicated that the PK mutation gene was spread by unregulated interbreeding.

Indexed as

Anemia, Hemolytic, Congenital NonspherocyticCat DiseasesHoardingAnimalsCatsJapanPyruvate KinasePyruvate Metabolism, Inborn ErrorsPyruvate Kinaseanimal hoarding catmicrosatellite markermutant allele frequencypyruvate kinase deficiencystray cat

Identifiers

PMID37495518
PMCPMC10539810
OpenAlexW4385267263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.