Evidence map›Paper›PMID 37495260›Full record

Observational studyBMJ open respiratory research2023

Prevalence of swallow, communication, voice and cognitive compromise following hospitalisation for COVID-19: the PHOSP-COVID analysis.

Camilla Dawson, Gemma Clunie, Felicity Evison, Sallyanne Duncan, Julie Whitney, Linzy Houchen-Wolloff, Charlotte E Bolton, Olivia C Leavy, Matthew Richardson, Elneima Omer and 39 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMJ open respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors at 20 institutions in 1 country.

Camilla DawsonDepartment of Speech and Language Therapy, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK camilla.dawson@nhs.net.ORCID 0000-0002-9910-666X
Gemma ClunieDepartment of Surgery and Cancer, Imperial College London, London, UK.
Felicity EvisonDepartment of Informatics, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.ORCID 0000-0002-9378-7548
Sallyanne DuncanWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.
Julie WhitneyKing's College London Faculty of Life Sciences and Medicine, London, UK.
Linzy Houchen-WolloffDepartment of Pulmonary Rehabilitation, University Hospitals of Leicester, Leicester, UK.
Charlotte E BoltonRespiratory Medicine, NIHR Nottingham Biomedical Research Centre Respiratory Theme, University of Nottingham, Nottingham, UK.ORCID 0000-0002-9578-2249
Olivia C LeavyDepartment of Health Sciences, University of Leicester, Leicester, UK.ORCID 0000-0002-1503-5535
Matthew RichardsonLeicester Respiratory Biomedical Research Unit, National Institute for Health Research, Leicester, UK.
Elneima OmerInstitute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Hamish McAuleyUniversity of Leicester, Leicester, UK.
Aarti ShikotraNIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Amisha SingapuriInstitute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Marco SerenoInstitute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Ruth M SaundersDepartment of Infection, Immunity and Inflammation, Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Victoria C HarrisInstitute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Neil J GreeningRespiratory Sciences, University of Leicester, Leicester, UK.ORCID 0000-0003-0453-7529
Claire Marie NolanRoyal Brompton and Harefield Hospitals, London, UK.
Dan Gower WoottonRespiratory Research, University Hospital Aintree, Liverpool, UK.
Enya DaynesCERS, NIHR Leicester Biomedical Research Centre, Leicester, UK.
Gavin DonaldsonImperial College London, London, UK.
Jack SargentUniversity Hospitals of Leicester NHS Trust, Leicester, UK.
Janet ScottUniversity of Glasgow, Glasgow, UK.
John PimmHealthy Minds, The Buckinghamshire IAPT Service, Oxford Health NHS Foundation Trust, Oxford, UK.
Lettie BishopLoughborough University, Loughborough, UK.
Melitta McNarryCollege of Engineering, Swansea University, Swansea, UK.
Nicholas HartLane Fox Respiratory Service, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Rachael A EvansUniversity of Leicester, Leicester, UK.ORCID 0000-0002-1667-868X
Sally SinghCardiac/Pulmonary Rehabilitation, University Hospitals of Leicester NHS Trust, Leicester, UK.
Tom YatesUniversity of Leicester, Leicester, UK.
Trudie ChalderKing's College London, London, UK.
William ManImperial College London, London, UK.
Ewen HarrisonUsher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
Annemarie DochertyUsher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
Nazir I LoneUsher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-2707-2779
Jennifer K QuintImperial College London, London, UK.
James ChalmersTayside Respiratory Research Group, University of Dundee, Dundee, UK.
Ling-Pei HoMRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford, UK.
Alex Robert HorsleyRespiratory Medicine, Manchester Adult Cystic Fibrosis Centre, Manchester, UK.ORCID 0000-0003-1828-0058
Michael MarksLondon School of Hygiene & Tropical Medicine, London, UK.
Krisnah PoinasamyHead of Research and Innovation Advocacy, Asthma UK, London, UK.
Betty RamanDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxfordshire, UK.
Louise V WainBiomedical Research Centre-Respiratory, National Institute for Health Research, Leicester, UK.
Chris BrightlingInstitute of Lung Health, University of Leicester, Leicester, UK.ORCID 0000-0002-5803-5121
PHOSP-COVID collaborative Group
Neil SharmaInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Margaret CoffeyImperial College London, London, UK.
Amit KulkarniRoyal College of Speech and Language Therapists, London, UK.
Sarah WallaceWythenshawe Hospital, Manchester, UK.
University of Leicester · GBImperial College London · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity Hospitals of Leicester NHS Trust · GBUniversity of Edinburgh · GBKing's College London · GBRoyal College of Speech and Language Therapists · GBAsthma UK · GBChurchill Hospital · GBCystic Fibrosis Trust · GBGuy's and St Thomas' NHS Foundation Trust · GBHarefield Hospital · GBLondon School of Hygiene & Tropical Medicine · GBLoughborough University · GBNational Institute for Health Research · GBNIHR Leicester Biomedical Research Centre · GBOxford Health NHS Foundation Trust · GBQueen's University Belfast · GBSwansea University · GBUniversity of Dundee · GB

Funding

Department of HealthMedical Research Council MR/V027859/1
6 · The paper itself

Abstract

objectiveIdentify prevalence of self-reported swallow, communication, voice and cognitive compromise following hospitalisation for COVID-19.

designMulticentre prospective observational cohort study using questionnaire data at visit 1 (2-7 months post discharge) and visit 2 (10-14 months post discharge) from hospitalised patients in the UK. Lasso logistic regression analysis was undertaken to identify associations.

setting64 UK acute hospital Trusts.

participantsAdults aged >18 years, discharged from an admissions unit or ward at a UK hospital with COVID-19.

main outcome measuresSelf-reported swallow, communication, voice and cognitive compromise.

resultsCompromised swallowing post intensive care unit (post-ICU) admission was reported in 20% (188/955); 60% with swallow problems received invasive mechanical ventilation and were more likely to have undergone proning (p=0.039). Voice problems were reported in 34% (319/946) post-ICU admission who were more likely to have received invasive (p<0.001) or non-invasive ventilation (p=0.001) and to have been proned (p<0.001). Communication compromise was reported in 23% (527/2275) univariable analysis identified associations with younger age (p<0.001), female sex (p<0.001), social deprivation (p<0.001) and being a healthcare worker (p=0.010). Cognitive issues were reported by 70% (1598/2275), consistent at both visits, at visit 1 respondents were more likely to have higher baseline comorbidities and at visit 2 were associated with greater social deprivation (p<0.001).

conclusionSwallow, communication, voice and cognitive problems were prevalent post hospitalisation for COVID-19, alongside whole system compromise including reduced mobility and overall health scores. Research and testing of rehabilitation interventions are required at pace to explore these issues.

Indexed as

COVID-19AdultAftercareCognitionCommunicationFemaleHospitalizationHumansMalePatient DischargePrevalenceProspective StudiesARDSCOVID-19critical carepneumonia

Identifiers

PMID37495260
PMCPMC10360430
OpenAlexW4385285089

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.