Evidence map›Paper›PMID 37494281›Full record

ArticleJournal of the American Chemical Society2023

Enantioselective Transfer Hydrogenative Cycloaddition Unlocks the Total Synthesis of SF2446 B3: An Aglycone of Arenimycin and SF2446 Type II Polyketide Antibiotics.

Nancy O Huynh, Tomáš Hodík, Michael J Krische

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nancy O HuynhDepartment of Chemistry, University of Texas at Austin, 105 E 24th Street, Austin, Texas 78712, United States.
Tomáš HodíkDepartment of Chemistry, University of Texas at Austin, 105 E 24th Street, Austin, Texas 78712, United States.ORCID 0000-0003-1168-886X
Michael J KrischeDepartment of Chemistry, University of Texas at Austin, 105 E 24th Street, Austin, Texas 78712, United States.ORCID 0000-0001-8418-9709

Funding

Polyketides via Redox-Triggered Alcohol C-H Functionalization.R01GM093905 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI KRISCHE, MICHAEL J · 2011 to 2024
$4.5M
NIGMS NIH HHS R01 GM093905
6 · The paper itself

Abstract

The first total synthesis and structure validation of an arenimycin/SF2446 type II polyketide is described, as represented by

Indexed as

Anti-Bacterial AgentsPolyketidesAminoglycosidesCatalysisCycloaddition ReactionStereoisomerismAminoglycosidesAnti-Bacterial AgentsarenimycinPolyketides

Identifiers

PMID37494281
PMCPMC10443208

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.