Evidence map›Paper›PMID 37494126›Full record

ReviewExpert review of respiratory medicine

Up-to-date guidance towards improving medication adherence in patients with chronic obstructive pulmonary disease.

Meredith A Case, Michelle N Eakin

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of respiratory medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. A Narrative Review of the Correlation Between Comorbidity and Acute Exacerbation of COPD Patients.International journal of chronic obstructive pulmonary disease · 2026
    Review
  2. Article
  3. Behavioral Phenotypes of Inhaler Technique and Adherence in COPD: A Cross-Sectional Study.International journal of chronic obstructive pulmonary disease · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Meredith A CaseDivision of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Michelle N EakinDivision of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
Longitudinal study of determinants of medication adherence in COPDR01HL128620 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI EAKIN, MICHELLE NUTTALL · 2016 to 2020
$3.5M
A Mixed Methods Evaluation of Developing COPD Exacerbations in the MARC CohortF32HL167418 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CASE, MEREDITH ANNE · 2023 to 2024
$128k
NHLBI NIH HHS F32 HL167418NHLBI NIH HHS R01 HL128620NHLBI NIH HHS T32 HL007534
6 · The paper itself

Abstract

introductionDespite efficacious treatment for chronic obstructive pulmonary disease (COPD), medication adherence remains quite poor, with most estimates based on electronic monitoring devices ranging from 20-30%. This degree of nonadherence represents a significant missed opportunity to realize the benefits of treatment of this disease. AREAS COVERED: In this article, we review research on the prevalence of nonadherence among patients with COPD, the association of nonadherence with health outcomes, barriers to adherence in this patient population, and potential interventions. EXPERT OPINION: Integrating research into practice involves assessing patients' adherence, identifying modifiable barriers to adherence, open discussion of these barriers with patients, and tailored interventions to address them. These interventions may include treatment of previously unrecognized comorbid disease, providing educational or behavioral interventions, optimizing prescribing strategies, use of adherence aids, or addressing cost and other access barriers. Electronic inhaler monitors are promising interventions for both monitoring and improving adherence. However, remaining concerns about integration into patient care, data management, cost, acceptability, and ethical and privacy issues must be overcome prior to their implementation in clinical practice.

Indexed as

Pulmonary Disease, Chronic ObstructiveAdministration, InhalationHumansMedication AdherenceNebulizers and VaporizersTreatment OutcomeChronic obstructive pulmonary diseasedigital healthelectronic monitorsmedication adherencemedication compliance

Identifiers

PMID37494126
PMCPMC10529685
OpenAlexW4385286065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.