Evidence map›Paper›PMID 37493876›Full record

ReviewMolecular biology reports2023

Molecular and biological factors in the prognosis of head and neck squamous cell cancer.

Sergei S Naumov, Denis E Kulbakin, Nadezhda V Krakhmal, Sergey V Vtorushin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Bioinformatics analysis revealsTranslational cancer research · 2024
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sergei S NaumovPathology Department, Siberian State Medical University, 2 Moskovsky trakt, Tomsk, 634050, Russia. serg.nau2011@gmail.com.ORCID http://orcid.org/0000-0003-3868-2310
Denis E KulbakinCancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences Tomsk, 5 Kooperativny Street, Tomsk, 634009, Russia.
Nadezhda V KrakhmalPathology Department, Siberian State Medical University, 2 Moskovsky trakt, Tomsk, 634050, Russia.
Sergey V VtorushinPathology Department, Siberian State Medical University, 2 Moskovsky trakt, Tomsk, 634050, Russia.
Russian Academy of Sciences · RUSiberian State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the review is to summarize available literary data on the role and prognostic value of molecular biological markers p53, UBE2C, CD147, STAT3, VEGF in the carcinogenesis of head and neck squamous cell carcinoma (HNSCC). To date, researches have been studying HNSCC molecular and genetic characteristics and obtaining information about new molecular biological markers that have different functional significance in tumor progression. This review presents current data on protein molecules involved in the HNSCC development, as well as in the formation of drug resistance mechanisms in tumors. The considered markers can be used not only for prognosis but also for developing a new approach to treatment, including patients resistant to therapy or recurrent HNSCC. However, the introduction of these markers into practice requires further examination of their functions and larger-scale studies.

Indexed as

Head and Neck NeoplasmsNeoplasms, Squamous CellBiological FactorsBiomarkersHumansNeoplasm Recurrence, LocalSquamous Cell Carcinoma of Head and NeckBiological FactorsBiomarkersHNSCCMolecular markersTumor progression

Identifiers

PMID37493876
OpenAlexW4385263932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.