Evidence map›Paper›PMID 37493471›Full record

ReviewThe Journal of endocrinology2023

Islet cells in human type 1 diabetes: from recent advances to novel therapies - a symposium-based roadmap for future research.

J Cantley, D L Eizirik, E Latres, C M Dayan

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

J CantleySchool of Medicine, University of Dundee, Dundee, United Kingdom of Great Britain and Northern Ireland.ORCID 0000-0003-2509-1271
D L EizirikULB Center for Diabetes Research, Université Libre de Bruxelles Faculté de Médecine, Bruxelles, Belgium.
E LatresJDRF International, New York, NY, USA.
C M DayanCardiff University School of Medicine, Cardiff, United Kingdom of Great Britain and Northern Ireland.
Breakthrough T1D · USCardiff University · GBUniversité Libre de Bruxelles · BEUniversity of Dundee · GB

Funding

Medical Research Council MR/W019590/1
6 · The paper itself

Abstract

There is a growing understanding that the early phases of type 1 diabetes (T1D) are characterised by a deleterious dialogue between the pancreatic beta cells and the immune system. This, combined with the urgent need to better translate this growing knowledge into novel therapies, provided the background for the JDRF-DiabetesUK-INNODIA-nPOD symposium entitled 'Islet cells in human T1D: from recent advances to novel therapies', which took place in Stockholm, Sweden, in September 2022. We provide in this article an overview of the main themes addressed in the symposium, pointing to both promising conclusions and key unmet needs that remain to be addressed in order to achieve better approaches to prevent or reverse T1D.

Indexed as

Diabetes Mellitus, Type 1Insulin-Secreting CellsIslets of LangerhansHumansautoimmunediabetesinsulin secretionisletpancreas

Identifiers

PMID37493471
PMCPMC10502961
OpenAlexW4385264777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.