Evidence map›Paper›PMID 37493245›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2023

Impact of short-term, pharmacological CARM1 inhibition on skeletal muscle mass, function, and atrophy in mice.

Erin K Webb, Sean Y Ng, Andrew I Mikhail, Derek W Stouth, Tiffany L vanLieshout, Anika L Syroid, Vladimir Ljubicic

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. PRMT3 and CARM1: Emerging Epigenetic Targets in Cancer.Journal of cellular and molecular medicine · 2025
    Review
  2. Review
  3. Article
  4. Epigenetics of Skeletal Muscle Atrophy.International journal of molecular sciences · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Erin K WebbDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada.
Sean Y NgDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada.
Andrew I MikhailDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-8977-2055
Derek W StouthDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada.
Tiffany L vanLieshoutDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada.
Anika L SyroidDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada.
Vladimir LjubicicDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-4592-4093
McMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coactivator-associated arginine methyltransferase 1 (CARM1) catalyzes the methylation of arginine residues on target proteins critical for health and disease. The purpose of this study was to characterize the effects of short-term, pharmacological CARM1 inhibition on skeletal muscle size, function, and atrophy. Adult mice (

Indexed as

Muscle, SkeletalProtein-Arginine N-MethyltransferasesAnimalsMaleMiceMuscular AtrophyProtein Bindingcoactivator-associated arginine methyltransferase 1Protein-Arginine N-Methyltransferasesarginine methylationautophagyexercisemitochondriaPRMT

Identifiers

PMID37493245
PMCPMC10625826
OpenAlexW4385264372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.