Evidence map›Paper›PMID 37493236›Full record

ArticleMolecular pharmaceutics2023

Comparing PVP and Polymeric Micellar Formulations of a PEGylated Photosensitizing Phthalocyanine by NMR and Optical Techniques.

Lea P Gergely, Çiğdem Yüceel, Ümit İşci, Florentin S Spadin, Lukas Schneider, Bernhard Spingler, Martin Frenz, Fabienne Dumoulin, Martina Vermathen

Open access · hybridAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Lea P GergelyDepartment of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern 3012, Switzerland.
Çiğdem YüceelDepartment of Chemical Engineering, Gebze Technical University, Gebze 41400 Kocaeli, Turkey.
Ümit İşciDepartment of Chemistry, Gebze Technical University, Gebze 41400 Kocaeli, Turkey.
Florentin S SpadinInstitute of Applied Physics, University of Bern, Bern 3012, Switzerland.
Lukas SchneiderDepartment of Chemistry, University of Zurich, Zurich 8057, Switzerland.ORCID 0000-0003-0052-4560
Bernhard SpinglerDepartment of Chemistry, University of Zurich, Zurich 8057, Switzerland.ORCID 0000-0003-3402-2016
Martin FrenzInstitute of Applied Physics, University of Bern, Bern 3012, Switzerland.
Fabienne DumoulinFaculty of Engineering and Natural Sciences, Biomedical Engineering Department, Acıbadem Mehmet Ali Aydınlar University, Ataşehir, Istanbul 34752, Turkey.ORCID 0000-0002-0388-8338
Martina VermathenDepartment of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern 3012, Switzerland.ORCID 0000-0002-0796-1643
University of Bern · CHGebze Technical University · TRUniversity of Zurich · CHKent Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phthalocyanines are ideal candidates as photosensitizers for photodynamic therapy (PDT) of cancer due to their favorable chemical and photophysical properties. However, their tendency to form aggregates in water reduces PDT efficacy and poses challenges in obtaining efficient forms of phthalocyanines for therapeutic applications. In the current work, polyvinylpyrrolidone (PVP) and micellar formulations were compared for encapsulating and monomerizing a water-soluble zinc phthalocyanine bearing four non-peripheral triethylene glycol chains (

Indexed as

MicellesPhotochemotherapyIsoindolesMagnetic Resonance SpectroscopyPhotosensitizing AgentsPolyethylene GlycolsPolyethylenesPolymersPolypropylenesPovidoneWaterIsoindolesMicellesPhotosensitizing AgentsphthalocyaninePolyethylene GlycolsPolyethylenesPolymersPolypropylenesPovidoneUCON 50-HB-5100Waterdrug deliveryfluorescence spectroscopyKolliphor RH40NMR spectroscopyphotosensitizerphthalocyaninepolymer micellesPVPtriblock copolymers

Identifiers

PMID37493236
PMCPMC10410667
OpenAlexW4385264324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.